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Mitochondrial nitric oxide in the signaling of cell integrated responses
(American Physiological Society, 2007-05-01)
Mitochondria are the specialized organelles for energy metabolism, but, as a typical example of system biology, they also activate a multiplicity of pathways that modulate cell proliferation and mitochondrial biogenesis ...
Potential utility of protein targets of cysteine-s-nitrosylation in identifying clinical disease status in human chagas disease
(Frontiers Media S.A., 2019-01)
Trypanosoma cruzi (Tc) infection causes Chagas disease (ChD) presented by dilated cardiomyopathy and heart failure. During infection, oxidative and nitrosative stresses are elicited by the immune cells for control the ...
Efecto de la restricción proteico-calórica prenatal y postnatal sobre el estrés oxidativo y nitrosativo a nivel mitocondrial
(Universidad Michoacana de San Nicolás de Hidalgo, 2009-02)
Nutrition in recent years has taken great interest as a determining factor in the development of chronic diseases and there is scientific evidence that dietary disturbances (malnutrition or obesity) have an influence on ...
The regulation of cell energetics and mitochondrial signaling by nitric oxide
(Academic Press, 2010)
The recognition that nitric oxide (NO) acts as a reversible inhibitor of cytochrome oxidase activity competitively with O 2 produced a Copernican revolution in the understanding of the regulation of respiration, especially ...
Cytoprotective mechanisms in rats lung parenchyma with zinc deprivation
(Springer, 2014-02-19)
Suboptimal intake of Zinc (Zn) is one of the most common worldwide nutritional problems. The aim of this study is to provide new evidence on the relation between moderate Zn restriction, and cytoprotective functions ...
Radical acylation of L-lysine derivatives and L-lysine-containing peptides by peroxynitrite-treated diacetyl and methylglyoxal
(Informa Healthcare, 2014-03-01)
Highly electrophilic alpha-dicarbonyls such as diacetyl, methylglyoxal, 3-deoxyglucosone, and 4,5- dioxovaleric acid have been characterized as secondary catabolites that can aggregate proteins and form DNA nucleobase ...
Role of PheE15 Gate in Ligand Entry and Nitric Oxide Detoxification Function of Mycobacterium tuberculosis Truncated Hemoglobin N
(Public Library of Science, 2012-11)
The truncated hemoglobin N, HbN, of Mycobacterium tuberculosis is endowed with a potent nitric oxide dioxygenase (NOD) activity that allows it to relieve nitrosative stress and enhance in vivo survival of its host. Despite ...
Rv2617c and P36 are virulence factors of pathogenic mycobacteria involved in resistance to oxidative stress
(Taylor & Francis, 2019-12)
In this study, we characterized the role of Rv2617c in the virulence of Mycobacterium tuberculosis. Rv2617c is a protein of unknown function unique to M. tuberculosis complex (MTC) and Mycobacterium leprae. In vitro, this ...
S-nitrosoglutathione incorporated in poly(ethylene glycol) matrix: potential use for topical nitric oxide delivery
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2004)