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Avaliação de modificações pós-traducionais de caráter redox do fungo Paracoccidioides brasiliensis após estresse nitrosativo
(Universidade Federal de São Paulo (UNIFESP), 2017-03-31)
The fungi Paracoccidioides brasiliensis and P. lutzii are the causative agents of paracoccidioidomycosis, a systemic mycosis endemic in Latin America. This fungus is considered a facultative intracellular pathogen, able ...
Activation of Survival and Apoptotic Signaling Pathways in Lymphocytes Exposed to Palmitic Acid
(WILEY-BLACKWELLMALDEN, 2012)
The toxicity of palmitic acid (PA) towards a human T-lymphocyte cell line (Jurkat) has been previously investigated but the mechanism(s) of PA action were unknown. In the current study, Jurkat cells were treated with ...
Galactomannan as a potential modulator of intestinal ischemia–reperfusion injury
(Academic Press Inc Elsevier Science, 2020-05-01)
Background: Galactomannan (GAL), a polysaccharide present on the cell wall of several fungi, has shown an ability to modulate inflammatory responses through the dectin-1 receptor in human macrophages. However, studies ...
Elevation of NO Increases Ca2+ Entry and Resting Ca2+ and Na+ Concentrations in Skeletal Muscle Cells
(Cell Press, 2015)
Protein S-nitrosylation is a reversible post-translational modification and can
have profound effects on protein function in skeletal muscle. S-nitrosylation
has been proposed to exert regulatory effects on ion channels ...
Novos mecanismos pelos quais o exercício físico melhora a resistência à insulina no músculo esquelético
(Sociedade Brasileira de Endocrinologia e Metabologia, 2009-06-01)
Insulin resistance of skeletal muscle glucose transport is a key-defect for the development of impaired glucose tolerance and type 2 diabetes. However, it is known that both an acute bout of exercise and chronic endurance ...
Alteration in the expression of inflammatory parameters as a result of oxidative stress produced by moderate zinc deficiency in rat lung
(Taylor & Francis, 2010-02)
Suboptimal intake of dietary zinc (Zn) is one of the most common nutritional problems worldwide. Previously, the authors have shown that zinc deficiency (ZD) produces oxidative and nitrosative stress in lung of male rats. ...
An Update on Environmental Stressors and Their Effects on Oxidative Parameters in Limpets
(Nova Science Publishers, 2016)
Intertidal limpets are subjected to several environmental changes, and how theselimpets cope with these stressful conditions plays a key role in the understanding of themechanisms leading to their habitat adaptation. The ...
S-nitrosoglutathione (GSNO) is cytotoxic to intracellular amastigotes and promotes healing of topically treated Leishmania major or Leishmania braziliensis skin lesions
(Oxford Univ PressOxfordInglaterra, 2013)