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Alternatives for the Treatment of Schistosomiasis: Physico-Chemical Characterization of an Inclusion Complex Between Praziquantel and Hydroxypropyl-beta-Cyclodextrin
(Colegio Farmaceuticos Provincia De Buenos AiresLa PlataArgentina, 2010)
Improvement of the oral praziquantel anthelmintic effect by cyclodextrin complexation
(Taylor & Francis Ltd, 2010-01-01)
Schistosomiasis is a parasitic disease which kills a half million people per year, a I I over the world. Praziquantel (PZQ) is the drug-of-choice for schistosomiasis because of its effectiveness, ease of administration, ...
Thermal characterization of solid lipid nanoparticles containing praziquantel
(Springer, 2012-04-01)
Solid lipid nanoparticles (SLNs), loaded and unloaded with praziquantel (PRZ-load SLN and PRZ-unload SLN) were prepared by two different procedures: (a) oil-in-water hot microemulsion method, obtaining at 70 degrees C an ...
Liposomal-praziquantel: Efficacy against Schistosoma mansoni in a preclinical assay
(2013-10-01)
Currently, schistosomiasis mansoni is treated clinically with praziquantel (PZQ). Nevertheless, cases of tolerance and resistance to this drug have been reported, creating the need to develop new drugs or to improve existing ...
Development and physicochemical characterization of solid dispersions containing praziquantel for the treatment of schistosomiasis
(2017-02-01)
Praziquantel (PZQ) is an anthelminthic agent active against parasitic flatworms of the Schistosoma type and the most important drug for the treatment and morbidity control of schistosomiasis. In this study, a high-performance ...
Altered Response of Strain of Schistosoma mansoni to Oxamniquine and Praziquantel
(Instituto Oswaldo Cruz, Ministério da Saúde, 2002)
Síntese do anti-helmíntico praziquantel, a partir da glicinaPraziquantel synthesis
(Sociedade Brasileira de Química, 1999)