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Analysis of HCV quasispecies dynamic under selective pressure of combined therapy
(2013-02-01)
Background: The quasispecies composition of Hepatitis C virus (HCV) could have important implications with regard to viral persistence and response to interferon-based therapy. The complete NS5A was analyzed to evaluate ...
Analysis of HCV quasispecies dynamic under selective pressure of combined therapy
(2013-02-01)
Background: The quasispecies composition of Hepatitis C virus (HCV) could have important implications with regard to viral persistence and response to interferon-based therapy. The complete NS5A was analyzed to evaluate ...
Multi-locus sequence analysis reveals profound genetic diversity among isolates of the human pathogen bartonella bacilliformis
(Public Library of Science, 2011)
Bartonella bacilliformis is the aetiological agent of human bartonellosis, a potentially life threatening infection of significant public health concern in the Andean region of South America. Human bartonellosis has long ...
A global reference for human genetic variation
(Springer Nature, 2015)
The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations. Here we report ...
HLA-G variability and haplotypes detected by massively parallel sequencing procedures in the geographicaly distinct population samples of Brazil and Cyprus
(2017-03-01)
The HLA-G molecule presents immunomodulatory properties that might inhibit immune responses when interacting with specific Natural Killer and T cell receptors, such as KIR2DL4, ILT2 and ILT4. Thus, HLA-G might influence ...
Phred-Phrap package to analyses tools: a pipeline to facilitate population genetics re-sequencing studies
(BioMed Central Ltd., 2014)
Macrogeographic genetic structure of Lutzomyia longipalpis complex populations using Next Generation Sequencing
(Public Library Science, 2019-10-03)
Lutzomyia longipalpis is the main vector of Leishmania infantum, the causative agent of visceral leishmaniasis in the Neotropical realm. Its taxonomic status has been widely discussed once it encompasses a complex of ...
On Hepatitis C Virus Evolution: The Interaction between Virus and Host towards Treatment Outcome
(2013-04-25)
Background:Hepatitis C is a disease spread throughout the world. Hepatitis C virus (HCV), the etiological agent of this disease, is a single-stranded positive RNA virus. Its genome encodes a single precursor protein that ...
On Hepatitis C Virus Evolution: The Interaction between Virus and Host towards Treatment Outcome
(2013-04-25)
Background:Hepatitis C is a disease spread throughout the world. Hepatitis C virus (HCV), the etiological agent of this disease, is a single-stranded positive RNA virus. Its genome encodes a single precursor protein that ...