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Now showing items 21-30 of 181
Minutes, days and years: molecular interactions among different scales of biological timing
(The Royal Society, 2014-01)
Biological clocks are genetically encoded oscillators that allow organisms to keep track of their environment. Among them, the circadian system is a highly conserved timing structure that regulates several physiological, ...
A combinatorial framework to quantify peak/pit asymmetries in complex dynamics
(Nature Publishing Group, 2018-12)
We explore a combinatorial framework which efficiently quantifies the asymmetries between minima and maxima in local fluctuations of time series. We first showcase its performance by applying it to a battery of synthetic ...
A Computational Theory for the Emergence of Grammatical Categories in Cortical Dynamics
(Frontiers Research Foundation, 2020-04)
A general agreement in psycholinguistics claims that syntax and meaning are unified precisely and very quickly during online sentence processing. Although several theories have advanced arguments regarding the neurocomputational ...
The role of heparan sulfates in protein aggregation and their potential impact on neurodegeneration
(Wiley, 2018-06)
Neurodegenerative disorders, such as Alzheimer´s, Parkinson´s, and prion diseases, are directly linked to the formation and accumulation of protein aggregates in the brain. These aggregates, principally made of proteins ...
Are changes in the wnt/b-catenin pathway involved in cocaine and stress-induced long-term neuroadaptations?
(Elyns Publishing group, 2017-10)
Drug addiction has been defined as a chronic relapsing brain disease, characterized by compulsive drug seeking and use, despite harmful consequences. This phenomenon has been extensively studied and the use of animal models ...
Regional brain susceptibility to neurodegeneration: What is the role of glial cells?
(Medknow Publications, 2020-05)
The main pathological feature of the neurodegenerative diseases is represented by neuronal death that represents the final step of a cascade of adverse/hostile events. Early in the neurodegenerative process, glial cells ...
Previous stress exposure enhances both anxiety-like behaviour and p35 levels in the basolateral amygdala complex: Modulation by midazolam
(Elsevier Science, 2010-06)
Stress exposure induces long lasting neurobiological changes in selected brain areas, which could be associated with the emergence of negative emotional responses. In the present study, previously restrained animals exhibited ...
Prenatal exposure to the CB1 and CB2 cannabinoid receptor agonist WIN 55,212-2 alters migration of early-born glutamatergic neurons and GABAergic interneurons in the rat cerebral cortex
(Wiley, 2014-05)
The endocannabinoid system, composed of cannabinoid receptors, endocannabinoids, and synthesis and degradation enzymes, is present since early stages of brain development. During this period, the endocannabinoid system is ...
Gazing behavior during problem solving tasks in domestic dogs. A critical review
(Edizioni ETS, 2018-08)
In the last few years, several studies have assessed dogs’ behavior when confronted with solvable or unsolvable tasks in the presence of human partners. In these situations, dogs tend to gaze towards people, which has been ...
An appetitive experience after fear memory destabilization attenuates fear retention: Involvement GluN2B-NMDA receptors in the basolateral amygdala complex
(Cold Spring Harbor Laboratory Press, 2016-09)
It is known that a consolidated memory can return to a labile state and become transiently malleable following reactivation. This instability is followed by a restabilization phase termed reconsolidation. In this work, we ...