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Intracellular Distribution and Involvement of GPR30 in the Actions of E2 on C2C12 Cells
(Wiley, 2015-09)
G-protein-coupled receptor 30 (GPR30) is an estrogen receptor that initiates several rapid, non-genomic signaling events triggered by E2.GPR30 has recently been identified in C2C12 cells; however, little is known about the ...
New mimetic peptides inhibitors of Аb aggregation. Molecular guidance for rational drug design
(Elsevier, 2015-05)
A new series of mimetic peptides possessing a significant Aβ aggregation modulating effect was reported here. These compounds were obtained based on a molecular modelling study which allowed us to perform a structural-based ...
Defective ubiquitination of cerebral proteins in Alzheimer's disease
(Wiley-liss, Div John Wiley & Sons Inc, 2000-10)
Alzheimer's disease (AD) is characterized by the presence of neurofibrillary tangles (NFT), senile plaques, and cerebrovascular deposits of amyloid-beta. Ubiquitin has also been shown to be present in some of the inclusions ...
Antithrombotic and Antioxidant Activity of Amaranth Hydrolysate Obtained by Activation of an Endogenous Protease
(Springer, 2016-06)
Ingestion of diets with antithrombotic and antioxidant components offer a convenient and effective way to prevent and reduce the incidence of cardiovascular diseases. The aim of the present work was to obtain an amaranth ...
Phenotypic detection of plasmid-mediated colistin resistance in Enterobacteriaceae
(American Society for Microbiology, 2019-12)
The aim of this work was to evaluate an easy-to-perform assay basedupon inhibition of mobile colistin resistance (MCR) activity by EDTA. We included 92nonrelated isolates of Enterobacteriaceae (74 Escherichia coli, 17 ...
Effects of chlorogenic acid on thermal stress tolerance in C. elegans via HIF-1, HSF-1 and autophagy
(Elsevier Gmbh, 2020-01)
Chlorogenic acid (CGA) is a polyphenol widely distributed in plants and plant-derived food with antioxidant and protective activities against cell stress. Caenorhabditis elegans is a model organism particularly useful for ...
Cryopreservation of dog spermatozoa: Effect of bovine serum albumin on acrosomal integrity and pregnancy rates after artificial insemination
(2007-12-31)
The objective of the present study was to compare the in vitro and in vivo profile of frozen dog semen with Tris-bovine serum albumin (TB) and Tris-egg yolk (TE) extenders. Twenty dogs were used as donors. Each dog was ...
Resistance of 43 Sugarcane Clones to Smut (Ustilago scitaminea Sydow)Título en español
(University of Puerto Rico Mayagüez Campus Agricultural Experiment Station, 1986)
Effect of prostaglandins on the production of H2O2 and cytokines that modulate the fungicidal activity of human monocytes against Paracoccidioides brasiliensis
(2006-04-26)
Human monocytes lack fungicidal activity against high virulent strains of Paracoccidioides brasiliensis, the etiological agent of paracoccidioidomycosis, even after IFN-γ activation. However, monocytes treated with ...
Comparative analysis of the pathological events involved in immune and non-immune TRALI models
(WILEY-BLACKWELLHOBOKEN, 2012)
Background and Objectives Transfusion-related acute lung injury (TRALI) is characterized by leukocyte transmigration and alveolar capillary leakage shortly after transfusion. TRALI pathogenesis has not been fully elucidated. ...