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A hydrogel scaffold that maintains viability and supports differentiation of dental pulp stem cells
(2013-01-01)
Objectives: The clinical translation of stem cell-based Regenerative Endodontics demands further development of suitable injectable scaffolds. Puramatrix™ is a defined, self-assembling peptide hydrogel which instantaneously ...
Recent advances in smart hydrogels for biomedical applications: From self-assembly to functional approaches
(2018-02-01)
This review discusses basic aspects used to control the architecture and functional properties of smart hydrogels. The introduction briefly outlines what has been accomplished regarding smart hydrogels and explores historical ...
A novel pH-responsive hydrogel-based on calcium alginate engineered by the previous formation of polyelectrolyte complexes (PECs) intended to vaginal administration
(2017-10-03)
This work aimed to develop a calcium alginate hydrogel as a pH responsive delivery system for polymyxin B (PMX) sustained-release through the vaginal route. Two samples of sodium alginate from different suppliers were ...
Formulation and characterization of hydrogel based on pectin and brea gum
(Elsevier Science, 2019-02)
A hydrogel is a three-dimensional network formed by flexible chains of polymers that absorb considerable amounts of water. The objectives of this work were to formulate hydrogels from pectin and brea gum and to study their ...
Preparation and characterisation of Dextran-70 hydrogel for controlled release of praziquantel
(Universidade de São Paulo (USP), Faculdade de Ciências Farmacêuticas, 2014)
Post-synthesis modification of hydrogels. Total and partial rupture of crosslinks: Formation of aldehyde groups and re-crosslinking of cleaved hydrogels
(Elsevier, 2017-03)
Post-synthesis modification of hydrogels is frequently used for chemical functionalization, immobilization of molecules or optimization of mechanical properties. In this work, novel gels were developed usinga divinyl ...
Polyacrylic acid polymers hydrogels intended to topical drug delivery: preparation and characterization
(Informa Healthcare, 2015-06-01)
Context: Bioadhesiviness of polyacrylic acid polymers make them promising hydrogels to design topical drug delivery systems, allowing a close contact with biological substrate as well as an enhanced local concentration ...
Injectable MMP-Responsive Nanotube-Modified Gelatin Hydrogel for Dental Infection Ablation
(Amer Chemical Soc, 2020-04-08)
A photocrosslinkable gelatin methacryloyl (GelMA) hydrogel has been widely examined in regenerative engineering because of its good cell-tissue affinity and degradability in the presence of matrix metalloproteinases. A ...
Fibronectin-loaded Collagen/Gelatin Hydrogel Is a Potent Signaling Biomaterial for Dental Pulp Regeneration
(2021-01-01)
Introduction: Guided tissue regeneration has been considered a promising biological strategy to replace conventional endodontic therapies of teeth with incomplete root formation. Therefore, in the present study, a ...