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Antinociceptive effects of methadone combined with detomidine or acepromazine in horses
(EVJ Ltd., 2015)
To investigate two protocols to provide antinociception in horses. To evaluate the antinociceptive effects of intravenous methadone combined with detomidine or acepromazine in adult horses. Randomised, blinded, crossover ...
Validation of mechanical, electrical and thermal nociceptive stimulation methods in horses
(EVJ Ltd., 2015)
To validate a model for investigating the effects of analgesic drugs on mechanical, thermal and electrical stimulation testing. To investigate repeatability, sensitivity and specificity of nociceptive tests. Randomised ...
Poly(lactic acid) composites based on graphene oxide particles with antibacterial behavior enhanced by electrical stimulus and biocompatibility
(Wiley, 2018)
Poly(lactic acid) (PLA) is a biodegradable and biocompatible polyester widely used in biomedical applications. Unfortunately, this biomaterial suffers from some shortcomings related with the absence of both bioactivity and ...
Sedative and antinociceptive effects of different detomidine constant rate infusions, with or without methadone in standing horses
(2019-07-01)
Background: Standing surgery avoids the risks of general anaesthesia in horses. Objectives: To assess sedation, antinociception and gastrointestinal motility in standing horses after a detomidine loading dose and 2-h ...
Sedative and antinociceptive effects of different combinations of detomidine and methadone in standing horses
(2017-09-01)
Objective To evaluate intravenous (IV) detomidine with methadone in horses to identify a combination which provides sedation and antinociception without adverse effects. Study design Randomized, placebo-controlled, blinded, ...