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Encapsulação da rifampicina em matrizes poliméricas flutuantes obtidas por liofilização a partir de metilcelulose e ftalato de hidroxipropilmetilcelulose. Avaliação da liberação in vitro
(2001-12-01)
Floating multiparticles for oral administration with different compositions were studied from a matricial polymeric system to obtain sustained release. The polymers used in the multiparticles constitution were methylceullose ...
The importance of bioactivation in computer-guided drug repositioning: Why the parent drug is not always enough
(Bentham Science Publishers, 2016-08)
Although bioactivation is a well-documented process and the role of active metabolites in the drug discovery field has long been recognized, drug metabolites are usually ignored in virtual screening campaigns oriented to ...
Validation of UV spectrophotometric method for determination of lomefloxacin in pharmaceutical dosage form
(2005-07-01)
A simple and reproducible method was developed for the assay of lomefloxacin in tablets. The excipients in the commercial tablet preparation did not interfere with the assay. Beer's law is obeyed in the range 2.0-9.0 μg.mL-1 ...
Validation of UV spectrophotometric method for determination of lomefloxacin in pharmaceutical dosage form
(2005-07-01)
A simple and reproducible method was developed for the assay of lomefloxacin in tablets. The excipients in the commercial tablet preparation did not interfere with the assay. Beer's law is obeyed in the range 2.0-9.0 μg.mL-1 ...
Preventable adverse drug events in critically ill HIV patients: is the detection of potential drug-drug interactions a useful tool?
(Faculdade de Medicina / USP, 2019)
Rational Pharmacotherapy in Infectious Diseases: Issues Related to Drug Residues in Edible Animal Tissues
(Multidisciplinary Digital Publishing Institute, 2021-10)
Drugs are used in veterinary medicine to prevent or treat animal diseases. When rationally administered to livestock following Good Veterinary Practices (GVP), they greatly contribute to improving the production of food ...