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Theoretical study of dopamine. Application of the HSAB principle to the study of drug-receptor interactions
(Elsevier, 2000)
We present a theoretical conformational study of neutral and N- protonated form of dopamine in which we relate its pharmacological activity to the chemical hardness. We have found that the neutral form presents small ...
Ethanol's Action Mechanisms in the Brain: From Lipid General Alterations to Specific Protein Receptor Binding
(2017-02-23)
Ethanol is the most popular addictive substance used in the word. Its small and relatively simple structure facilitates its access to brain tissues and binding to many sites. This relatively unspecific action can partially ...
Advances in prodrug design
(2005-10-01)
The background of prodrug design is presented herein as the basis for introducing new and advanced latent systems, taking into account mainly the versatility of polymers and other macromolecules as carriers. PDEPT ...
Advances in prodrug design
(2005-10-01)
The background of prodrug design is presented herein as the basis for introducing new and advanced latent systems, taking into account mainly the versatility of polymers and other macromolecules as carriers. PDEPT ...
Advances in prodrug design
(2014)
Flavonoids as GABAA receptor ligands: the whole story?
(Dove Medical Press, 2012-01)
Benzodiazepines are the most widely prescribed class of psychoactive drugs in current therapeutic use, despite the important unwanted side effects that they produce, such as sedation, myorelaxation, ataxia, amnesia, and ...
Assessment of in vitro pharmacological effect of Neotropical Piperaceae in GABAergic bioassays in relation to plants traditionally used for folk illness by the Yanesha (Peru)
(Elsevier, 2014)
A previous pilot ethnobotanical and ethnopharmacological study with the Q‘echi׳ Maya identified the family Piperaceae, as an important taxonomic group traditionally used for the treatment of epileptic and culture-bound ...
Coumarins and adenosine receptors: New perceptions in structure–affinity relationships
(Blackwell Publishing Ltd, 2018)