We present a theoretical conformational study of neutral and N- protonated form of dopamine in which we relate its pharmacological activity to the chemical hardness. We have found that the neutral form presents small ...

Ethanol is the most popular addictive substance used in the word. Its small and relatively simple structure facilitates its access to brain tissues and binding to many sites. This relatively unspecific action can partially ...

The background of prodrug design is presented herein as the basis for introducing new and advanced latent systems, taking into account mainly the versatility of polymers and other macromolecules as carriers. PDEPT ...

The background of prodrug design is presented herein as the basis for introducing new and advanced latent systems, taking into account mainly the versatility of polymers and other macromolecules as carriers. PDEPT ...

Benzodiazepines are the most widely prescribed class of psychoactive drugs in current therapeutic use, despite the important unwanted side effects that they produce, such as sedation, myorelaxation, ataxia, amnesia, and ...

A previous pilot ethnobotanical and ethnopharmacological study with the Q‘echi׳ Maya identified the family Piperaceae, as an important taxonomic group traditionally used for the treatment of epileptic and culture-bound ...