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Now showing items 11-20 of 24
Enhanced nicotine-seeking behavior following pre-exposure to repeated cocaine is accompanied by changes in BDNF in the nucleus accumbens of rats
(2013-03-01)
We investigated the behavioral and molecular interactions between cocaine and nicotine, through evaluating locomotor activity, nicotine intravenous self-administration and gene expression. Locomotor sensitization was induced ...
Anxiogenic and antinociceptive effects induced by corticotropin-releasing factor (CRF) injections into the periaqueductal gray are modulated by CRF1 receptor in mice
(Academic Press Inc. Elsevier B.V., 2011-08-01)
Chemical or electrical stimulation of the dorsal portion of the midbrain periaqueductal gray (dPAG) produces anxiogenic and antinociceptive effects. In rats, chemical stimulation of dPAG by local infusion of the neuropeptide ...
Pituitary-adrenal activity and opioid release in ponies during thiopentone/halothane anaesthesia
(1995-02-01)
The effect of thiopentone/halothane anaesthesia on the release of endogenous opioid, adrenocorticotrophin, arginine vasopressin, cortisol and catecholamine was investigated in ponies. The contribution made by halothane ...
Total intravenous anaesthesia in ponies using detomidine, ketamine and guaiphenesin: Pharmacokinetics, cardiopulmonary and endocrine effects
(1995-10-16)
Pharmacokinetics and some pharmacological effects of anaesthesia induced by a combination of detomidine, ketamine and guaiphenesin were investigated in eight ponies. Cardiopulmonary function was studied and plasma ...
Depressão e estresse: existe um endofenótipo?
(Associação Brasileira de Psiquiatria - ABP, 2007-05-01)
OBJECTIVE: To review the new findings about stress, hypothalamic-pituitary-adrenal axis and depression trying to explain a possible endophenotype prone to depression. METHOD: Nonsystematic review of the literature based ...
Cardiorespiratory, endocrine and metabolic changes in ponies undergoing intravenous or inhalation anaesthesia
(1996-08-21)
Six Welsh gelding ponies (weight 246 ± 6 kg) were premedicated with 0.03 mg/kg of acepromazine intravenously (i.v.) followed by 0.02 mg/kg of detomidine i.v. Anaesthesia was induced with 2 mg/kg of ketamine i.v. Ponies ...
Neuroendocrine and Peptidergic Regulation of Stress-Induced REM Sleep Rebound
(Frontiers Media Sa, 2016)
Sleep homeostasis depends on the length and quality (occurrence of stressful events, for instance) of the preceding waking time. Forced wakefulness (sleep deprivation or sleep restriction) is one of the main tools used for ...
Secretion of metalloendopeptidase 24.15 (EC 3.4.24.15)
(Mary Ann Liebert, Inc., 1999-10-01)
The metalloendopeptidase EP24.15 (EC3.4.24.15) is a neuropeptide-metabolizing enzyme present in neural and endocrine tissues, presumably functioning extracellularly, Because the majority of the EP24.15 activity is identified ...
CRF family peptides are differently altered by acute restraint stress and chronic unpredictable stress
(Elsevier B.V., 2014-09-01)
Corticotropin-releasing factor (CRF) acts to promote stress-like physiological and behavioral responses and is mainly expressed in the paraventricular hypothalamic nucleus (PVN). Urocortin 1 (Ucn1) is also a ligand to CRF ...