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Aerobic exercise upregulates the BDNF-Serotonin systems and improves the cognitive function in rats
(Academic Press Inc Elsevier Science, 2018-11)
Aerobic exercise (AE) benefits brain health and behavior. Serotonin (5-HT) and brain-derived neurotrophic factor (BDNF) are known to mediate and shape cognitive processes. Both systems share some actions: BDNF is involved ...
Causal Shannon-Fisher characterization of motor/imagery movements in EEG
(Molecular Diversity Preservation International, 2018-09)
The electroencephalogram (EEG) is an electrophysiological monitoring method that allows us to glimpse the electrical activity of the brain. Neural oscillations patterns are perhaps the best salient feature of EEG as they ...
Are Glial Cells Critical Participants in Brain Development, Function, and Disease?
(OMINCS, 2012-09)
Recently, an increasing number of studies have implicated a third element in plasticity; the perisynaptic glial cell. Originally glial cells were thought to be important for metabolic maintenance and support of Central The ...
P66Shc Inactivation modifies RNS production, regulates Sirt3 activity, and improves mitochondrial homeostasis, delaying the aging process in mouse brain
(Landes Bioscience, 2018-03)
Programmed and damage aging theories have traditionally been conceived as stand-alone schools of thought. However, the p66Shc adaptor protein has demonstrated that aging-regulating genes and reactive oxygen species (ROS) ...
Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed
(Cell Press, 2014-12)
Circular RNAs (circRNAs) are an endogenous class of animal RNAs. Despite their abundance, their function and expression in the nervous system are unknown. Therefore, we sequenced RNA from different brain regions, primary ...
Immune-mediated loss of transgene expression from virally transduced brain cells is irreversible, mediated by IFNγ, perforin, and TNFα, and due to the elimination of transduced cells
(The American Society of Gene & Cell Therapy, 2012-01)
The adaptive immune response to viral vectors reduces vector-mediated transgene expression from the brain. It is unknown, however, whether this loss is caused by functional downregulation of transgene expression or death ...
Scale-Free Dynamics in Animal Groups and Brain Networks
(Frontiers Media, 2021-01-20)
Collective phenomena fascinate by the emergence of order in systems composed of a myriad of small entities. They are ubiquitous in nature and can be found over a vast range of scales in physical and biological systems. ...
Response to the Letter to the Editor: "Mitochondria isolated from the striatum of the brain exhibit a higher degree of oxidative phosphorylation coupling, which shows that they are not subject to energetic dysfunction upon acute paraquat administration"
(Springer/Plenum Publishers, 2016-12)
In his Letter to the Editor, Professor Rendon states that our published work entitled “Impairment of striatal mitochondrial function by acute paraquat poisoning”, published in J Bioenerg Biomembr 2015; 47(5): 395–408, a ...
Expression of coat proteins changes during postnatal development in selected areas of the rat brain
(Pergamon-Elsevier Science Ltd, 2012-06)
It is well known that clathrin-mediated endocytosis is crucial for the normal functioning and integrity of neurons in the central nervous system. In this study we attempted to correlate the expression of coat proteins with ...
Induction of ABCG2/BCRP restricts the distribution of zidovudine to the fetal brain in rats
(Academic Press Inc Elsevier Science, 2017-09)
Safety concerns for fetus development of zidovudine (AZT) administration as prophylaxis of vertical transmission of HIV persist. We evaluated the participation of the ATP-binding cassette efflux transporter ABCG2 in the ...