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Praziquantel systems with improved dissolution rate obtained by high pressure homogenization
(Elsevier Science, 2018-12-01)
Praziquantel (PZQ), an antihelmintic agent commonly administered to humans and cattle, has low aqueous solubility, which compromises its bioavailability and efficacy. The purpose of this study was to develop a new formulation, ...
Amaranth proteins emulsions as delivery system of Angiotensin-I converting enzyme inhibitory peptides
(Elsevier, 2019-05)
We analyze the possibility of using the emulsifying properties of amaranth proteins and the bioactivity shown by peptide sequences encrypted in these proteins to formulate functional emulsions with angiotensin I-converting ...
Intraspecific variation in mercury, δ 15 N, and δ 13 C among three Adélie Penguin (Pygoscelis adeliae) populations in the northern Antarctic Peninsula region
(Society of Environmental Toxicology and Chemistry, 2021-07)
Mercury (Hg) is a pervasive environmental contaminant that accumulates in the organs and tissues of seabirds at concentrations capable of causing acute or long-term adverse health effects. In this study, Hg concentrations ...
In vitro experiments and infrared spectroscopy analysis of acid and alkaline phosphatase inhibition by vanadium complexes
(Royal Society of Chemistry, 2019-05)
In the course of our research of vanadium-containing complexes, two oxidovanadium complexes containing vanadium(V) and (IV) core with 4-aminobenzoic acid and/or peroxo anion as ligands were synthesized and characterized ...
Recent advances in the development of “curcumin inspired” compounds as new therapeutic agents
(Bentham Science Publishers, 2020-10)
Despite a huge body of research in the past two decades investigating the antioxidant, anti-inflammatory, anti-microbial, and anti-carcinogenic properties of curcumin (CUR), a CUR-based anti-tumor drug is yet to be developed. ...
Egg albumin-folic acid nanocomplexes: Performance as a functional ingredient and biological activity
(Elsevier, 2015-10)
The ability of egg white (EW) nanoparticles to bind folic acid (FA) and protect it through the gastrointestinal tract and the resulting properties of the mixtures as functional ingredient was investigated. Two kinds of EW ...
Pharmacokinetics of levofloxacin after single intravenous, oral and subcutaneous administration to dogs
(Wiley Blackwell Publishing, Inc, 2018-10)
The pharmacokinetic properties of the fluoroquinolone levofloxacin (LFX) were investigated in six dogs after single intravenous, oral and subcutaneous administration at a dose of 2.5, 5 and 5 mg/kg, respectively. After ...
Hypertension, nitric oxide, oxidants, and dietary plant polyphenols
(Bentham Science Publishers, 2010-07)
Fruits and vegetables are key foods whose high ingestion is associated with the improvement of numerous pathological conditions, including hypertension. Such health promoting actions have been increasingly ascribed to the ...
Mitochondrial function and nitric oxide metabolism are modified by enalapril in rat kidney
(American Physiological Society, 2007-04)
The renal and cardiac benefits of renin-angiotensin system (RAS) inhibition in hypertension exceed those attributable to blood pressure reduction, and seem to involve mitochondrial function changes. To investigate whether ...
Taxonomic and functional approach of subtidal macrobenthic communities in the Bahía Blanca Estuary (Argentina)
(Springer, 2021)
The macrobenthic communities in the soft-bottom subtidal areas of the Bahía Blanca Estuary are dominated by polychaetes, crustaceans, and mollusks. Species richness, abundance, biomass, and taxonomic and functional diversity ...