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Anticoagulants interfere with the angiogenic and regenerative responses mediated by platelets
(Frontiers Media, 2020-03-20)
Background and aims: Platelet rich plasma (PRP) obtained from blood anticoagulated with acid-citrate-dextrose (ACD) or sodium-citrate (SC) is used for regenerative medicine as source of platelet-derived growth factors. ...
Prevención secundaria de la trombosis en pacientes con síndrome antifosfolípido
(Sociedad de Neurología, Psiquiatría y Neurocirugía, 2003)
Ultra-low-molecular-weight heparins: Precise structural features impacting specific anticoagulant activities
(Schattauer Gmbh-verlag Medizin Naturwissenschaften, 2013-03-01)
Ultra-low-molecular-weight heparins (ULMWHs) with better efficacy and safety ratios are under development; however, there are few structural data available. the main structural features and molecular weight of ULMWHs were ...
Drug-drug interactions affecting drug levels of direct oral anticoagulants in the real world: A systematic review
Background: Direct oral anticoagulants (DOACs) have emerged as safe and effective
alternatives to Vitamin-K antagonists for treatment and prevention of arterial and venous
thrombosis. Due to their novelty, pharmacokinetic ...
Intermolecular interactions and characterization of the novel factor Xa exosite involved in macromolecular recognition and inhibition: Crystal structure of human Gla-domainless factor Xa complexed with the anticoagulant protein NAPc2 from the hematophagous nematode Ancylostoma caninum
(Elsevier B.V., 2007-02-16)
NAPc2, an anticoagulant protein from the hematophagous nematode Ancylostoma caninum evaluated in phase-II/IIa clinical trials, inhibits the extrinsic blood coagulation pathway by a two step mechanism, initially interacting ...
Na2EDTA anticoagulant impaired blood samples from the teleost Piaractus Mesopotamicus
(2016-05-01)
The present study aimed to evaluate the effects of Na heparin and Na2EDTA on blood of Piaractus mesopotamicus (360.7±42.4g, 26.4±1.0cm). Twenty fishes were sampled in two experiment trials, ten for erythrocyte fragility ...