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Topical interleukin-1 receptor antagonist inhibits inflammatory cell infiltration into the cornea
(ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 2008)
Interleukin (IL)-1 alpha and beta are important modulators of many functions of corneal epithelial and stromal cells that occur following injury to the cornea, including the influx of bone marrow-derived inflammatory cells ...
A suicide attempt with an oral calcium channel blocker
(COMPARATIVE TOXICOLOGY LAB, 2000)
Calcium channel blockers are widely used in all-aged populations. The drugs are generally safe in therapeutic dosage, but severe side effects with elevated intake are increasingly described, mainly in adult patients. We ...
Influence of size and duration of gynecomastia on its response to treatment with tamoxifen Terapia médica de la ginecomastia con tamoxifeno. Influencia del volumen y duración de la ginecomastia en el resultado terapéutico
(2007)
Background: Gynecomastia is treated when it is painful, there are psychosocial repercussions or it does not revert in less tan two years. It is treated with the antiestrogenic drug tamoxifen, but there are doubts about its ...
Novel 2-(substituted benzyl)quinuclidines inhibit human α7 and α4β2 nicotinic receptors by different mechanisms
(Elsevier, 2013-08)
This work presents the design and synthesis of a series of novel 2-benzylquinuclidine derivatives, comprising 12 methiodide and 11 hydrochloride salts, and their structural and pharmacological characterization at the human ...
Spinal Effects of the Fesoterodine Metabolite 5-Hydroxymethyl Tolterodine and/or Doxazosin in Rats With or Without Partial Urethral Obstruction
(Elsevier B.V., 2010-08-01)
Purpose: the combination of muscarinic receptor and alpha(1)-radrenoceptor antagonists is increasingly used for benign prostatic hyperplasia related lower urinary tract symptoms. in addition to the well established peripheral ...
Ghrelin antagonist regulates metabolic hormone receptorsin the hypothalamus of ewes
(Elsevier, 2020-04)
This study evaluates the effects of ghrelin antagonist on mRNA abundance for metabolic hormone receptors in feed-restricted ewes. Ewes were randomly assigned to one of three treatments; Control (CO): feed above maintenance ...