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Alpha7 Nicotinic Acetylcholine Receptor Expression and Activity During Neuronal Differentiation of PC12 Pheochromocytoma Cells
(HUMANA PRESS INC, 2010)
Nicotinic acetylcholine receptors (nAChR) exert pivotal roles in synaptic transmission, neuroprotection and differentiation. Particularly, homomeric alpha 7 receptors participate in neurite outgrowth, presynaptic control ...
Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells.
(2014)
Cumulative evidence indicates that Wnt pathways play crucial and diverse roles to assemble the neuromuscular junction (NMJ), a peripheral synapse characterized by the clustering of acetylcholine receptors (AChR) on ...
Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells.
(2014)
Cumulative evidence indicates that Wnt pathways play crucial and diverse roles to assemble the neuromuscular junction (NMJ), a peripheral synapse characterized by the clustering of acetylcholine receptors (AChR) on ...
In silico characterization of cytisinoids docked into an acetylcholine binding protein
(PERGAMON-ELSEVIER SCIENCE LTD, 2010-05-06)
Homology models of nicotinic acetylcholine receptors (nAChRs) suggest that subtype specificity is due to
non-conserved residues in the complementary subunit of the ligand-binding pocket. Cytisine and its
derivatives ...
Activity of cytisine and its brominated isosteres on recombinant human α7, α4β2 and α4β4 nicotinic acetylcholine receptors
(2001)
Effects of cytisine (cy), 3-bromocytisine (3-Br-cy), 5-bromocytisine (5-Br-cy) and 3,5-dibromocytisine (3,5-diBr-cy) on human (h) α7-, α4β2- and α4β4 nicotinic acetylcholine (nACh) receptors, expressed in Xenopus oocytes ...
A deep learning-based approach to model anomalous diffusion of membrane proteins: The case of the nicotinic acetylcholine receptor
(Oxford University Press, 2021-10)
We present a concatenated deep-learning multiple neural network system for the analysis of single-molecule trajectories. We apply this machine learning-based analysis to characterize the translational diffusion of the ...
Mechanism of acetylcholine-induced calcium signaling during neuronal differentiation of P19 embryonal carcinoma cells in vitro
(CHURCHILL LIVINGSTONE, 2008)
Muscarinic (mAChRs) and nicotinic acetylcholine receptors (nAChRs) are involved in various physiological processes, including neuronal development. We provide evidence for expression of functional nicotinic and muscarinic ...
Erythrina mulungu Alkaloids Are Potent Inhibitors of Neuronal Nicotinic Receptor Currents in Mammalian Cells
(Public Library Science, 2013-12-13)
Crude extracts and three isolated alkaloids from Erythrina mulungu plants have shown anxiolytic effects in different animal models. We investigated whether these alkaloids could affect nicotinic acetylcholine receptors and ...
Neurotransmission in the carotid body: transmitters and modulators between glomus cells and petrosal ganglion nerve terminals
(ELSEVIER SCIENCE BV, 2004-12)
The carotid body (CB) is the main arterial chemoreceptor. The most accepted model of arterial chemoreception postulates that carotid body glomus (type 1) cells are the primary receptors, which are synaptically connected ...