Now showing items 21-30 of 69
Non-lobar atelectasis generates inflammation and structural alveolar injury in the surrounding healthy tissue during mechanical ventilation
Abstract Introduction When alveoli collapse the traction forces exerted on their walls by adjacent expanded units may increase and concentrate. These forces may promote its ...
Decreased lung compliance increases preload dynamic tests in a pediatric acute lung injury model
(Sociedad Chilena de Pediatría. Publicado por Elsevier España, S.L.U., 2015)
BACKGROUND: Preload dynamic tests, pulse pressure variation (PPV) and stroke volume variation (SVV) have emerged as powerful tools to predict response to fluid administration. The influence of factors other than preload ...
A physiological approach to understand the role of respiratory effort in the progression of lung injury in SARS-CoV-2 infection
Abstract Deterioration of lung function during the first week of COVID-19 has been observed when patients remain with insufficient respiratory support. Patient self-inflicted lung injury (P-SILI) is theorized as the ...
Impact of High-Intensity-NIV on the heart in stable COPD: a randomised cross-over pilot study
Abstract Background Although high-intensity non-invasive ventilation has been shown to improve outcomes in stable COPD, it may adversely affect cardiac performance. Therefore, ...
A randomized placebo-controlled phase II study of a Pseudomonas vaccine in ventilated ICU patients
Abstract Background Currently, no vaccine against Pseudomonas is available. IC43 is a new, recombinant, protein (OprF/I)-based vaccine against the opportunistic pathogen, ...