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Changes in the TNF-alpha/IL-10 ratio in hyperglycemia-associated pregnancies
(Elsevier B.V., 2015-03-01)
Aims: TNF-alpha is a diabetogenic cytokine associated with adverse outcomes during pregnancy that can be counterbalanced by IL-10. We have investigated IL-10 and TNF-alpha balance at maternal and placental levels in ...
Effects of Coccoloba uvifera L. on UV-stimulated melanocytes
(Wiley-Blackwell, 2008-12-01)
Exposure to ultraviolet (UV) radiation induces generation of reactive oxygen species, production of proinflammatory cytokines and melanocyte-stimulating hormone (MSH) as well as increase in tyrosinase activity. The potential ...
TNF-alpha, H2O2 and NO response of peritoneal macrophages to Yersinia enterocolitica O : 3 derivatives
(Elsevier B.V., 2004-02-01)
In this study, the effect of Yersinia derivatives on nitric oxide (NO), hydrogen peroxide (H2O2) and tumor necrosis factor-alpha (TNF-alpha) production by murine peritoneal macrophages was investigated. Addition of ...
IL-6 and TNF-alpha production during active canine visceral leishmaniasis
(Elsevier B.V., 2007-01-15)
We investigated the production of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) during canine visceral leishmaniasis (VL) to gain a better understanding of the role of such multi-functional cytokines in ...
Correlation between serum tumor necrosis factor alpha levels and clinical severity of tuberculosis
(Brazilian Society of Infectious Diseases, 2008)
This study verified the correlation between the serum levels of TNF alpha and different clinical forms of tuberculosis. We described a group of 24 patients presenting several clinical forms of tuberculosis and a control ...
TNF-alpha Infusion Impairs Corpora Cavernosa Reactivity
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
Introduction. Erectile dysfunction (ED), as well as cardiovascular diseases (CVDs), is associated with endothelial dysfunction and increased levels of proinflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha). ...
Tumor necrosis factor-alpha in gestation and puerperium of women with gestational hypertension and pre-eclampsia
(Blackwell Publishing, 2007-03-01)
Problem High plasma levels of tumor necrosis factor-alpha (TNF-alpha) in pregnant women have been associated with the pathogenesis of pre-eclampsia (PE). This study evaluated TNF-alpha plasma levels and monocyte production ...
Identification of the Schistosoma mansoni TNF-Alpha Receptor Gene and the Effect of Human TNF-Alpha on the Parasite Gene Expression Profile
(PUBLIC LIBRARY SCIENCE, 2009)
Background: Schistosoma mansoni is the major causative agent of schistosomiasis. The parasite takes advantage of host signals to complete its development in the human body. Tumor necrosis factor-alpha (TNF-alpha) is a human ...
Inhibition of hydrogen peroxide, nitric oxide and TNF-alpha production in peritoneal macrophages by ethyl acetate fraction from Alchornea glandulosa
(Pharmaceutical Soc Japan, 2005-09-01)
The effects of Alchornea glandulosa ethyl acetate fraction (AGF) on hydrogen peroxide (H2O2), nitric oxide (NO) and tumor necrosis factor-alpha (TNF-alpha) production in peritoneal macrophages activated with lipopolysaccharide ...
TNF-alpha acts in the hypothalamus inhibiting food intake and increasing the respiratory quotient - Effects on leptin and insulin signaling pathways
(Elsevier B.V., 2007-05-01)
Acting in the hypothalamus, tumor necrosis factor-alpha (TNF-alpha) produces a potent anorexigenic effect. However, the molecular mechanisms involved in this phenomenon are poorly characterized. In this study, we investigate ...