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Senescent CD4+CD28− T lymphocytes as a potential driver of Th17/Treg imbalance and alveolar bone resorption during periodontitis
(MDPI, 2022)
Senescent cells express a senescence-associated secretory phenotype (SASP) with a pro-inflammatory bias, which contributes to the chronicity of inflammation. During chronic inflammatory diseases, infiltrating CD4(+) T ...
Regulatory T cells and IgE expression in duodenal mucosa of Strongyloides stercoralis and human T lymphotropic virus type 1 co-infected patients
(Public Library of Science, 2019)
BACKGROUND: Strongyloides stercoralis is an intestinal nematode unique in its ability to replicate in the human host, allowing ongoing cycles of autoinfection, persisting for decades within the same host. Although usually ...
The role of regulatory t lymphocytes in the induced immune response mediated by biological vaccines
(ELSEVIER GMBH, URBAN & FISCHER VERLAG, 2006)
Immunotherapy has become a novel therapeutic alternative for various kinds of tumours. Recently, we have finalized the first phase I clinical study in Chile for the treatment of advanced malignant melanoma, using dendritic ...
Cancer immunotherapy–related adverse events: causes and challenges
(Springer, 2020-12)
Despite the success and ongoing promise of monoclonal antibody–targeted immune checkpoint inhibitor immunotherapy of advanced malignancies, in particular, antibodies directed against CTLA-4 and PD-1/PD-L1, the development ...
Signal integration duringT lymphocyte activation and function: lessons from the Wiskott–Aldrich syndrome
(University of Washington, 2015)
Type and Intensity as Key Variable of Exercise in Metainflammation Diseases: A Review
(2022-01-01)
Monocyte and lymphocyte subpopulations exhibit functions that vary between the anti- and pro-inflammatory spectrum, such as classic CD16- and non-classical CD16+monocytes, as well as T helper 2 lymphocytes (Th2), the ...
Regulatory T Cells Phenotype in Different Clinical Forms of Chagas Disease
(Public Library of Science, 2014)
Role of dendritic cells in the induction of lymphocyte tolerance
(2015)
The ability of dendritic cells (DCs) to trigger tolerance or immunity is dictated by the context in which an antigen is encountered. A large body of evidence indicates that antigen presentation by steady-state DCs induces ...
T-lymphocyte phenotype and function triggered by Aggregatibacter actinomycetemcomitans is serotype-dependent
(Blackwell Munksgaard, 2015)
& Sons Ltd. Background and Objective: Based on lipopolysaccharide (LPS) antigenicity, different Aggregatibacter actinomycetemcomitans serotypes have been described. Serotype b strains have demonstrated a stronger capacity ...