Now showing items 21-30 of 289
Mucoadhesive beads of gellan gum/pectin intended to controlled delivery of drugs
(Elsevier B.V., 2014-11-26)
Gellan gum/pectin beads were prepared by ionotropic gelation, using Al3+ as crosslinker. High yield (92.76%) and entrapment efficiency (52.22-88.78%) were reached. Beads exhibited high circularity (0.730-0.849) and size ...
Colloidal carriers for ophthalmic drug delivery
(Bentham Science Publ Ltd, 2005-05-01)
To achieve effective drug concentration at the intended site for a sufficient period of time is a requisite desired for many drug formulations. For drugs intended to ocular delivery, its poor bioavailability is due to ...
Highly Controlled Diffusion Drug Release from Ureasil-Poly(ethylene oxide)-Na+-Montmorillonite Hybrid Hydrogel Nanocomposites
In this work, we report the effects of incorporation of variable amounts (1-20 wt %) of sodium montmorillonite (MMT) into a siloxane-poly(ethylene oxide) hybrid hydrogel prepared by the sol-gel route. The aim was to control ...
Desenvolvimento e avaliação de um sistema de liberação sustentada de gentamicina em biomembranas de látex natural
(Universidade Estadual Paulista (UNESP), 2016)
Natural latex films as carrier for casearia sylvestris swartz extract associated with ciprofloxacin
In order to create a new sustained drug delivery system applied for tissue regeneration, this study beget a natural rubber latex (NRL) film with Casearia sylvestris extract and ciprofloxacin. Manipulated from the biomaterial ...
In vitro conditions for the study of the in vivo performance of sustained-release theophylline matrix tablets administered in fasted conditions and with a high-fat diet
(Marcel Dekker Inc., 1999)
Dissolution profiles of theophylline (TP) from three types of sustained- release (SR) matrix tablets (plastic [PL], lipid [LP], and hydrophilic [HP]) in different dissolution media, with and without enzymes, were established. ...
Desenvolvimento de um novo adesivo à base de látex natural carreado com ibuprofeno para tratamento de processos inflamatórios
(Universidade Estadual Paulista (UNESP), 2019-02-26)
A liberação sustentada de fármacos é um tópico importante para várias aplicações em nanotecnologia devido ao seu potencial impacto na sociedade, como a criação de sistemas de carreadores otimizados. A relevância dos sistemas ...
New formulation of an old drug in hypertension treatment: the sustained release of captopril from cyclodextrin nanoparticles
(Dove Medical Press LtdAlbanyNova Zelândia, 2011)
Development of egg PC/cholesterol/alpha-tocopherol liposomes with ionic gradients to deliver ropivacaine
(Taylor & Francis Ltd, 2016-01-02)
Context: Ropivacaine (RVC) is an aminoamide local anesthetic widely used in surgical procedures. Studies with RVC encapsulated in liposomes and complexed in cyclodextrins have shown good results, but in order to use RVC ...