Now showing items 1-10 of 5468
Sinergystic effects of steroidal glycosides of Solanum upon Human A375 Melanoma cells. A comparison with 1 Ketoconazole
(Facultad Experimental de Ciencias de la Universidad del Zulia, 2017)
Increase of leishmanicidal and tubercular activities using steroids linked to aminoquinoline
Background: Aminoquinoline/steroid conjugates were synthesized based on the fact that steroid transporters have been shown to accept and carry a variety of drugs. So, in continuing our research of antileishmanial and ...
Molecular properties of steroids involved in their effects on the biophysical state of membranes
(Elsevier Science, 2015-08)
The activity of steroids on membranes was studied in relation to their ordering, rigidifying, condensing and/or raft promoting ability. The structures of 82 steroids were modeled by a semi-empirical procedure (AM1) and 245 ...
Steroid diversification by multicomponent reactions
Reports on structural diversification of steroids by means of multicomponent reactions (MCRs) have significantly increased over the last decade. This review covers the most relevant strategies dealing with the use of ...
Separation of steroid isomers by ion mobility mass spectrometry
(Elsevier Science BvAmsterdamHolanda, 2013)
Circulating gonadal and adrenal steroids in amyotrophic lateral sclerosis: possible markers of susceptibility and outcome
(Georg Thieme Verlag Kg, 2014-05-07)
Although changes of circulating steroids have been reported in patients with sporadic amyotrophic lateral sclerosis (ALS), a full comparison of the adrenal and gonadal steroid profile between control subjects and ALS ...
Endometrium and steroids, a pathologic overview
Normal endometrial function requires of cell proliferation and differentiation; therefore, disturbances in these processes could lead to pathological entities such as hyperplasia and endometrial adenocarcinoma, where cell ...
Neuropeptide and steroid hormone mediators of neuroendocrine regulation
To maintain the health and well-being of all mammals, numerous aspects of physiology are controlled by neuroendocrine mechanisms. These mechanisms ultimately enable communication between neurones and glands throughout the ...
Structure-activity relationships of neuroactive steroids acting on the GABAA receptor
(Bentham Science Publishers, 2009-12)
The term "neuroactive steroid" (NAS) refers to steroids which, independent of their origin, are capable of modifying neural activities. These steroids positively or negatively modulate the function of members of the ...
Steroids differentially inhibit the nicotinic acetylcholine receptor
(Lippincott Williams, 2001-12-02)
The effect of various natural and synthetic steroids on the function of the nicotinic acetylcholine receptor (AChR) was studied at the single-channel level. AChR channel kinetics was affected by some substitutions in the ...