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Nasal eosinophilia: an indicator of eosinophilic inflammation in asthma
(WILEY-BLACKWELL, 2010)
Background It is noteworthy that there is a clear clinical, epidemiological and pathophysiological association between upper and lower airway inflammation in rhinitis and asthma. Objective The aim of this study was to ...
Relationship between induced sputum cytology and inflammatory status with lung structural and functional abnormalities in asbestosis
(WILEY-LISS, 2008)
Background Asbestosis is associated with lung cellular and immunological abnormalities. Induced sputum cytology and local and systemic markers of inflammation may be helpful to characterize disease status and progression ...
CPAP Has No Effect on Clearance, Sputum Properties, or Expectorated Volume in Cystic Fibrosis
(DAEDALUS ENTERPRISES INCIRVING, 2013-08-02)
BACKGROUND: Positive expiratory pressure (PEP) is used for airway clearance in cystic fibrosis (CF) patients. Hypertonic saline (HTS) aerosol increases sputum expectoration volume and may improve respiratory secretion ...
Rapid diagnosis of coccidioidomycosis by nested PCR assay of sputum
(Blackwell Publishing, 2007-04-01)
Coccidioidomycosis is a deep infection caused by two dimorphic fungi, Coccidioides immitis and Coccidioides posadasii. Diagnosis of the disease requires culture of suspicious clinical samples on mycological media. However, ...
Direct determination of pyrazinamide (PZA) susceptibility by sputum microscopic observation drug susceptibility (MODS) culture at neutral pH: the MODS-PZA assay
(American Society for Microbiology, 2020)
Pyrazinamide (PZA) is considered the pivot drug in all tuberculosis treatment regimens, due to its particular action on the persistent forms of Mycobacterium tuberculosis. However, no drug susceptibility test (DST) is ...
Analysis of aberrant methylation on promoter sequences of tumor suppressor genes and total DNA in sputum samples: A promising tool for early detection of COPD and lung cancer in smokers
(2012)
Background: Chronic obstructive pulmonary disease (COPD) is a disorder associated to cigarette smoke and lung cancer (LC). Since epigenetic changes in oncogenes and tumor suppressor genes (TSGs) are clearly important in ...