Now showing items 31-40 of 1786
Alternative splicing: The lord of the rings
(Macmillan Publishers Limited, 2017-05)
Circular RNAs can regulate the alternative splicing profile of their parental genes by physically interacting with the DNA to form RNA:DNA hybrids.
CTCF: from insulators to alternative splicing regulation
(Nature Publishing Group, 2012-02)
The zinc-finger DNA-binding protein CTCF has been known for being a constituent of insulators. A recent paper in Nature reports an unforeseen intragenic role for CTCF that links DNA methylation with alternative splicing. ...
A Long Noncoding Way to Alternative Splicing in Plant Development
(Cell Press, 2014-07)
In this issue of Developmental Cell, Bardou et al. (2014) elucidate how long, highly structured noncoding RNAs control alternative splicing regulators that specifically mediate the action of the hormone auxin in the promotion ...
Flexural strength characterisation of oblique radiata pine splice joints
Sawn timber is marketed in limited length, so larger construction sizes require structural joining solutions for discrete elements. Traditional carpentry joints allow wood elements to be joined in a sustainable way, as ...
Alternative splicing adds a new loop to the circadian clock
(Landes Bioscience, 2011-05)
Circadian clocks allow organisms to adjust multiple physiological and developmental processes in anticipation of daily and seasonal changes in the environment. At the molecular level these clocks consist of interlocked ...
The carboxy terminal domain of RNA polymerase II and alternative splicing
(Cell Press, 2010-09)
Alternative splicing is controlled by cis-regulatory sequences present in the pre-mRNA and their cognate trans-acting factors, as well as by its coupling to RNA polymerase II (pol II) transcription. A unique feature of ...
How Are Short Exons Flanked by Long Introns Defined and Committed to Splicing?
(Elsevier Science London, 2016-10)
The splice sites (SSs) delimiting an intron are brought together in the earliest step of spliceosome assembly yet it remains obscure how SS pairing occurs, especially when introns are thousands of nucleotides long. Splicing ...
Linking transcription, RNA polymerase II elongation and alternative splicing
(Journal of the Serbian Chemical Society, 2020-08-28)
Gene expression is an intricately regulated process that is at the basis of cell differentiation, the maintenance of cell identity and the cellular responses to environmental changes. Alternative splicing, the process by ...
Differential expression of new LTA splice variants upon lymphocyte activation
(Elsevier B.V., 2008-01-01)
Lymphotoxin alpha (LTA) is a member of the TNF cytokine superfamily, produced principally by lymphocytes. It plays an important role in immune and inflammatory responses. Many TNF superfamily members have functionally ...
Landscape of the spliced leader trans-splicing mechanism in Schistosoma mansoni
(Nature Publishing Group, 2019)