Now showing items 21-30 of 1786
Heteroduplex formation and S1 digestion for mapping alternative splicing sites
The identification of alternatively spliced transcripts has contributed to a better comprehension of developmental mechanisms, tissue-specific physiological processes and human diseases. Polymerase chain reaction amplification ...
Rhythmic behavior is controlled by the SRm160 splicing factor in Drosophila melanogaster
(Genetics Society of America, 2017-10)
Circadian clocks organize the metabolism, physiology, and behavior of organisms throughout the day–night cycle by controlling daily rhythms in gene expression at the transcriptional and post-transcriptional levels. While ...
Footprints of a trypanosomatid RNA world: pre-small subunit rRNA processing by spliced leader addition trans-splicing
(FUNDACO OSWALDO CRUZRIO DE JANEIRO, 2013-08-02)
The addition of a capped mini-exon [spliced leader (SL)] through trans-splicing is essential for the maturation of RNA polymerase (pol) II-transcribed polycistronic pre-mRNAs in all members of the Trypanosomatidae family. ...
Characterization of Three cDNAs obtained by spliced Leader-PCR screening of a Taenia solium cDNA library
(Universidad Nacional, Costa Rica, 2022)
The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators
(Oxford University Press, 2016-10-17)
Alternative splicing (AS) is a key component of gene expression programs that drive cellular differentiation. Smooth muscle cells (SMCs) are important in the function of a number of physiological systems; however, investigation ...
Epigenetics in Alternative Pre-mRNA Splicing
(Cell Press, 2011-01)
Alternative splicing plays critical roles in differentiation, development, and disease and is a major source for protein diversity in higher eukaryotes. Analysis of alternative splicing regulation has traditionally focused ...
Chromatin, DNA structure and alternative splicing
(Elsevier Science, 2015-06)
Coupling of transcription and alternative splicing via regulation of the transcriptional elongation rate is a well-studied phenomenon. Template features that act as roadblocks for the progression of RNA polymerase II ...
Osteopontin-c isoform levels are associated with SR and hnRNP differential expression in ovarian cancer cell lines
(Springer Verlag (Germany), 2017)
Identification of SL addition trans-splicing acceptor sites in the internal transcribed spacer I region of pre-rRNA in Leishmania (Leishmania) amazonensis
(Instituto Oswaldo Cruz, Ministério da Saúde, 2012)
Trypanosomatidae is a family of early branching eukaryotes harbouring a distinctive repertoire of gene expression strategies. Functional mature messenger RNA is generated via the trans-splicing and polyadenylation processing ...