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Screening and characterization of mutations in isoniazid-resistant Mycobacterium tuberculosis isolates obtained in Brazil
(Amer Soc Microbiology, 2004-09-01)
We investigated mutations in the genes katG, inhA (regulatory and structural regions), and kasA and the oxyR-ahpC intergenic region of 97 isoniazid (INH)-resistant and 60 INH-susceptible Mycobacterium tuberculosis isolates ...
Depressão e ansiedade na adolescência: o papel do baixo peso ao nascer e dos polimorfismos no sistema galaninérgico
(Universidade Federal de São Paulo (UNIFESP), 2016-11-30)
This thesis has been divided into two chapters. In the first chapter, the objective was to determine whether adolescents, with a history of low birth weight, are more likely to report symptoms of depression/anxiety. ...
Genome-enabled prediction of meat and carcass traits using Bayesian regression, single-step genomic best linear unbiased prediction and blending methods in Nelore cattle
(2021-01-01)
Several methods have been used for genome-enabled prediction (or genomic selection) of complex traits, for example, multiple regression models describing a target trait with a linear function of a set of genetic markers. ...
Avaliação de polimorfismos funcionais nos genes de reparo XRCC1, APEX1, XPD e XPF em carcinomas de células escamosas orais
(Universidade Federal do Rio Grande do NorteBrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM PATOLOGIA ORAL, 2015-02-24)
Base excision repair (BER) and nucleotide excision repair (NER) pathways play
critical role in maintaining genome integrity. Polymorphisms in BER and NER genes
which modulate the DNA repair capacity may affect the ...
Alternative methodologies for genotyping polymorphisms in the CAST and CAPN1 genes in beef cattle
(Brazilian Journal of Animal Science, 2023)
Human population genetic structure detected by pain-related mu opioid receptor gene polymorphisms
(Sociedade Brasileira de Genética, 2015-06)
Several single nucleotide polymorphisms (SNPs) in the Mu Opioid Receptor gene (OPRM1) have been identified and associated with a wide variety of clinical phenotypes related both to pain sensitivity and analgesic requirements. ...
Bovine thyroglobulin gene polymorphisms and their association with sexual precocity in Guzerat bulls
(Wiley Blackwell Publishing, Inc, 2017-10)
Puberty is a stage of sexual development determined by the interaction of environmental factors and genetic mechanisms. Among them, thyroid function plays a key role in sexual development and spermatogenic function and is ...
Glutathione-related genetic polymorphisms are associated with mercury retention and nephrotoxicity in gold-mining settings of a Colombian population Open Access
(Reino Unido, 2021-04-22)
Mercury (Hg) vapor can produce kidney injury, where the proximal tubule region of the nephron is the main target of the Hg-induced oxidative stress. Hg is eliminated from the body as a glutathione conjugate. Thus, single ...