Buscar
Mostrando ítems 31-40 de 313
A snake venom secreted phospholipase A2 induces foam cell formation depending on the activation of factors involved in lipid homeostasis
(2018-06)
MT-III, a snake venom GIIA sPLA2, which shares structural and functional features with mammalian GIIA sPLA2s, activates
macrophage defense functions including lipid droplet (LDs) formation, organelle involved in both lipid ...
The bactericidal effect of human secreted group IID phospholipase A(2) results from both hydrolytic and non-hydrolytic activities
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIERPARIS, 2012)
The Human Secreted Group IID Phospholipase A(2) (hsPLA2GIID) may be involved in the human acute immune response. Here we have demonstrated that the hsPLA2GIID presents bactericidal and Ca2+-independent liposome membrane-damaging ...
Lys49 myotoxins, secreted phospholipase A2-like proteins of viperid venoms: a comprehensive review
(2023)
Muscle necrosis is a potential clinical complication of snakebite envenomings, which in severe cases can lead to functional or physical sequelae such as disability or amputation. Snake venom proteins with the ability to ...
Mapping of suramin binding sites on the group IIA human secreted phospholipase A(2)
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2009)
Suramin is a polysulphonated napthylurea used as an antiprotozoal/anthelminitic drug, which also inhibits a broad range of enzymes. Suramin binding to recombinant human secreted group IIA phospholipase A(2) (hsPLA(2)GIIA) ...
Pichia pastoris engineering for the production of a modified phospholipase C
(Elsevier, 2016-12)
Crude vegetable oils are refined to remove impurities that adversely impact in their stability, color and flavor. In recent years, enzymatic degumming methods using phospholipase C (PLC) enzymes provide an environmentally ...
Bacterial Sphingomyelinases and Phospholipases as Virulence Factors
(2016-06-15)
Bacterial sphingomyelinases and phospholipases are a heterogeneous group of esterases which are usually surface associated or secreted by a wide variety of Gram-positive and Gram-negative bacteria. These enzymes hydrolyze ...