Now showing items 1-10 of 503
Repressor element-1 silencing transcription/neuron-restrictive silencer factor is required for neural sodium channel expression during development of Xenopus
The ability of neurons to fire rapid action potential relies on the expression of voltage-gated sodium channels; the onset of the transcription of genes that encode these channels occurs during early neuronal development. ...
Interaction between brain L-type calcium channels and alpha(2)-adrenoceptors in the inhibition of sodium appetite
(Elsevier B.V., 2002-03-22)
Calcium channels mediate the actions of many drugs. The present work investigated whether diltiazem, an L-type calcium channel blocker, alters the inhibition of sodium appetite induced by noradrenaline and the alpha(2)-a ...
Mineralocorticoids modulate the expression of the β-3 subunit of the Na+, K+-ATPase in the renal collecting duct
(Taylor and Francis Inc., 2017)
© 2017 Taylor & Francis. Renal sodium reabsorption depends on the activity of the Na+,K+-ATPase α/β heterodimer. Four α (α1–4) and 3 β (β1–3) subunit isoforms have been described. It is accepted that renal tubule cells ...
Mineralocorticoids modulate the expression of the b-3 subunit of the Na+, K+ - ATPase in the renal collecting duct
(Taylor & Francis, 2017)
Renal sodium reabsorption depends on the activity of the Na+,K+-ATPase / heterodimer. Four ((1-4)) and 3 ((1-3)) subunit isoforms have been described. It is accepted that renal tubule cells express (1)/(1) dimers. Aldosterone ...
Batrachotoxin-modified sodium channels from squid optic nerve in planar bilayers: Ion conduction and gating properties
Squid optic nerve sodium channels were characterized in planar bilayers in the presence of batrachotoxin (BTX). The channel exhibits a conductance of 20 pS in symmetrical 200 mM NaCI and behaves as a sodium electrode. The ...
Anestésicos locais: interação com membranas biológicas e com o canal de sódio voltagem-dependente
(Sociedade Brasileira de Química, 2008-01-01)
Many theories about the mechanism of action of local anesthetics (LA) are described in the literature. Two types of theories can be distinguished: those that focus on the direct effects of LA on their target protein in the ...