Now showing items 1-10 of 1403
Differential RNA sequence requirement for dengue virus replication in mosquito and mammalian cells
(American Society for Microbiology, 2013-08)
Dengue virus cycles between mosquitoes and humans. Each host provides a different environment for viral replication, imposing different selective pressures. We identified a sequence in the dengue virus genome that is ...
Long-Range RNA-RNA Interactions Circularize the Dengue Virus Genome
(American Society for Microbiology, 2005-05)
Secondary and tertiary RNA structures present in viral RNA genomes play essential regulatory roles during translation, RNA replication, and assembly of new viral particles. In the case of flaviviruses, RNA-RNA interactions ...
Dynamic RNA structures in the dengue virus genome
(Landes Bioscience, 2011)
Dengue virus is an important human pathogen that belongs to the Flaviviridae family. The viral genome is a single molecule of RNA of positive polarity that plays multiple roles during the viral life cycle. Besides encoding ...
A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases
(Frontiers Research Foundation, 2017-01)
Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize ...
Novel ATP-independent RNA annealing activity of the dengue virus NS3 helicase
(Public Library Of Science, 2012-04)
The flavivirus nonstructural protein 3 (NS3) bears multiple enzymatic activities and represents an attractive target for antiviral intervention. NS3 contains the viral serine protease at the N-terminus and ATPase, RTPase, ...
Dados preliminares sobre partículas semelhantes a virus em células de triatomíneosPreliminary data on particles similar to viruses in the cells of triatomines
(Faculdade de Saúde Pública da Universidade de São Paulo, 1978)
Some Physicochemical Properties of Maize Rayado Fino Virus
Maize rayado fino virus (RFV) was purified from infected maize (Zea mays) leaves. The virus had two components: empty shells and complete virus particles with sedimentation coefficients of 54S and 120S respectively, and ...
F1 Motif of Dengue Virus Polymerase NS5 Is Involved in Promoter-Dependent RNA Synthesis
(American Society For Microbiology, 2011-06)
The mechanism by which viral RNA-dependent RNA polymerases (RdRp) specifically amplify viral genomes is still unclear. In the case of flaviviruses, a model has been proposed that involves the recognition of an RNA element ...
Role of RNA structures present at the 3′UTR of dengue virus on translation, RNA synthesis, and viral replication
(Academic Press Inc Elsevier Science, 2005-09)
We have developed a dengue virus replicon system that can be used to discriminate between translation and RNA replication. Using this system, we analyzed the functional role of well-defined RNA elements present at the 3'UTR ...