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Analysis of the RNAome associated to the HIV-1 Rev protein during viral replica on in T-cells
(2018)
AIDS has become one of the most devastating pandemics in recorded history. The causal agent of AIDS is the human
immunodeficiency virus type-1 (HIV-1) that infects and destroys CD4+ T lymphocytes. Once integrated into the ...
Inibição do vírus da hepatite C utilizando siRNAs direcionados para o genoma viral e proteínas celulares Hsps
(Universidade Estadual Paulista (Unesp), 2013-08-23)
Hepatitis C is a consequence of infection by hepatitis C virus (HCV) and it is estimated that approximately 150 million people are chronically infected worldwide. Several studies have demonstrated interactions between viral ...
Avances y limitaciones en el uso de los dsRNA como estrategias de control y prevención de enfermedades virales en sistemas acuícolas
(Univ. Católica de Valparaíso, 2015)
El desarrollo de la acuicultura sustentable es acorde con la demanda creciente de nuevas metodologías que aseguren la salud de las diversas especies acuícolas. Dentro de ellas, el uso de terapias revolucionarias basadas ...
Overlapping local and long-range RNA-RNA interactions modulate dengue virus genome cyclization and replication
(American Society For Microbiology, 2015-03)
The dengue virus genome is a dynamic molecule that adopts different conformations in the infected cell. Here, using RNA folding predictions, chemical probing analysis, RNA binding assays, and functional studies, we identified ...
Psicobirnavírus: um novo vírus animal, características gerais, infecção experimental em ratos e estudos epidemiológicos em suínos
(Universidade Federal de São Paulo (UNIFESP), 1994)
Uncovering viral protein-protein interactions and their role in arenavirus life cycle
(MDPI, 2012-09)
The Arenaviridae family includes widely distributed pathogens that cause severe hemorrhagic fever in humans. Replication and packaging of their single-stranded RNA genome involve RNA recognition by viral proteins and a ...
Detection of hepatitis C virus RNA by in situ hybridization in paraformaldehyde fixed biopsies
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2020)