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A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases
(Frontiers Research Foundation, 2017-01)
Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize ...
Role of the Dengue Virus 5' and 3' Untranslated Regions in Viral Replication
(Caister Academic Press, 2010)
As for all plus-stranded RNA viruses, dengue virus (DENV) genomic RNA is infectious. Transfection of full length DENV RNA genome into a susceptible cell triggers a complete cycle of viral replication. Construction of cDNA ...
Molecular characterization of IPNV RNA replication intermediates during the viral infective cycle
(2009)
Infectious Pancreatic Necrosis Virus (IPNV) is a bisegmented, double-stranded RNA virus, which belongs to the Birnaviridae family. In the current study, we have analyzed the RNA replication intermediates (RI) purified ...
Metagenomic insights into the sewage RNA virosphere of a large city
(MDPI, 2020)
Sewage-associated viruses can cause several human and animal diseases, such as gastroenteritis, hepatitis, and respiratory infections. Therefore, their detection in wastewater can reflect current infections within the ...
Differential RNA sequence requirement for dengue virus replication in mosquito and mammalian cells
(American Society for Microbiology, 2013-08)
Dengue virus cycles between mosquitoes and humans. Each host provides a different environment for viral replication, imposing different selective pressures. We identified a sequence in the dengue virus genome that is ...
Interactions between the HIV-1 unspliced mRNA and host mRNA decay machineries
(MDPI AG, 2016)
© 2016 by the authors; licensee MDPI, Basel, Switzerland. The human immunodeficiency virus type-1 (HIV-1) unspliced transcript is used both as mRNA for the synthesis of structural proteins and as the packaged genome. Given ...
Estructuras de RNA y su impacto sobre el inicio de la traducción del mRNA genómico de HIV-1 y del SmRNA de ANDV.RNA structures and their impact on the translation initiation from the the HIV-1 genomic mRNA and the ANDV SmRNA.
(2019)
La síntesis de proteínas es el proceso por el cual la información contenida en un RNA mensajero (mRNA) es decodificada para sintetizar la correspondiente cadena polipeptídica. El proceso de síntesis de proteínas se divide ...
The presence of m6A within the 5 ?-UTR of the HIV-1 genomic RNA defines its use as mRNA or as the packaged genome
(2018)
The human immunodeficiency virus type 1 (HIV-1) is the etiological agent of the acquired immunodeficiency syndrome
(AIDS). Their genome consists of a positive sense RNA (genomic RNA or gRNA), which is found as a dimer ...
The RNA-dependent RNA polymerase of the infectious pancreatic necrosis virus is linked to viral mRNA acting as a cap substitute
(2022)
The infectious pancreatic necrosis virus (IPNV) is responsible for significant economic losses in the aquaculture industry. It is an unenveloped virus with an icosahedral capsid. Its viral genome comprises two dsRNA segments, ...