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Estimation of the Minimum Number of Replication Origins Per Chromosome in any Organism
(Bio-protocol, 2020-10-20)
Eukaryote nuclear genomes predominantly replicate through multiple replication origins. The number of replication origins activated per chromosome during the S-phase duration may vary according to many factors, but the ...
Hepatitis C virus in vitro replication is efficiently inhibited by acridone Fac4
(2017-07-01)
Hepatitis C virus (HCV) affects about 170 million people worldwide. The current treatment has a high cost and variable response rates according to the virus genotype. Acridones, a group of compounds extracted from natural ...
FBH1 mediates DNA double strand breakage and apoptosis in response to DNA replication stress
(Rockefeller Univ Press, 2013-01)
Proper resolution of stalled replication forks is essential for genome stability. Purification of FBH1, a UvrD DNA helicase, identified a physical interaction with replication protein A (RPA), the major cellular singlestranded ...
MutS regulates access of the error-prone DNA polymerase Pol IV to replication sites: a novel mechanism for maintaining replication fidelity
(Oxford University Press, 2016-09)
Translesion DNA polymerases (Pol) function in the bypass of template lesions to relieve stalled replication forks but also display potentially deleterious mutagenic phenotypes that contribute to antibiotic resistance in ...
Replications of fundamental research models in ultra high dilutions 1994 and 2015-update on a bibliometric study
(Elsevier B.V., 2015-10-01)
Introduction: This paper focuses exclusively on experimental models with ultra high dilutions (i.e. beyond 10(-23)) that have been submitted to replication scrutiny. It updates previous surveys, considers suggestions made ...
Precision of Usual Food Intake Estimates According to the Percentage of Individuals with a Second Dietary Measurement
(ELSEVIER SCIENCE INCNEW YORK, 2012)
Background Statistical methods for estimating usual intake require at least two short-term dietary measurements in a subsample of the target population. However, the percentage of individuals with a second dietary measurement ...
The chromatin structure of the lysozyme GAS41 origin of DNA replication changes during the cell cycle
(Sociedad de Biología de Chile, 2007)
Biological evolution of replicator systems: towards a quantitative approach
(SpringerDordrecht, 2013)
The aim of this work is to study the features of a simple replicator chemical model of the relation between kinetic stability and entropy production under the action of external perturbations. We quantitatively explore the ...
Client-side selection of replicated web services: An empirical assessment
(Elsevier Science IncNew YorkEUA, 2008)