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NMR as a tool for simultaneous study of diasteroisomeric inclusion complexes, part 2: Complexes formed by racemic mixture of 4′- hydroxyflavanone and two cyclodextrins
(2012)
Complexes formed by (±)-4′-hydroxyflavanone (OHFL) and the cyclodextrins β-cyclodextrin and (2-hydroxypropyl)-β-CD were obtained using the racemic mixture of the OHFL. These complexes were able to be studied due to their ...
Stereochemical nomenclature: racemization and resolution [Freshman organic chemistry]
(Yale University, Open Yale Courses, 2016)
Pharmacokinetic implications associated to the use of drugs as racemates or pure enantiomers Implicancias farmacocinéticas asociadas al uso de fármacos como racematos o enantiómeros puros.
(1995)
This article critically reviews the recent specialized literature concerning the influence of the stereochemical nature of quiral drugs on the pharmacokinetic processes and its pharmacological implications. Evidence is ...
Absolute Configuration and Selective Trypanocidal Activity of Gaudichaudianic Acid Enantiomers
(Amer Chemical Soc, 2011-05-01)
Gaudichaudianic acid, a prenylated chromene isolated from Piper gaudichaudianum, has been described as a potent trypanocidal compound against the Y-strain of Trypanosoma cruzi. We herein describe its isolation as a racemic ...
Absolute Configuration and Selective Trypanocidal Activity of Gaudichaudianic Acid Enantiomers
(Amer Chemical Soc, 2011-05-01)
Gaudichaudianic acid, a prenylated chromene isolated from Piper gaudichaudianum, has been described as a potent trypanocidal compound against the Y-strain of Trypanosoma cruzi. We herein describe its isolation as a racemic ...
Resolution and Absolute Configuration Assignment of a Natural Racemic Chromane from Peperomia obtusifolia (Piperaceae)
(Wiley-liss, 2009-10-01)
The resolution of the natural racemic chromane 3,4-dihydro-5-hydroxy-2,7-dimethyl-8-(3 ''-methyl-2 ''-butenyl)-2-(4'-methyl-1',3'-pentadienyl)-2H-1-benzopyran-6-carboxylic acid (1) isolated from the leaves of Peperomia ...
Resolution and Absolute Configuration Assignment of a Natural Racemic Chromane from Peperomia obtusifolia (Piperaceae)
(Wiley-liss, 2009-10-01)
The resolution of the natural racemic chromane 3,4-dihydro-5-hydroxy-2,7-dimethyl-8-(3 ''-methyl-2 ''-butenyl)-2-(4'-methyl-1',3'-pentadienyl)-2H-1-benzopyran-6-carboxylic acid (1) isolated from the leaves of Peperomia ...
Influence of gasoline inhalation on the enantioselective pharmacokinetics of fluoxetine in rats
(2013-03-01)
Fluoxetine is used clinically as a racemic mixture of (+)-(S) and (-)-(R) enantiomers for the treatment of depression. CYP2D6 catalyzes the metabolism of both fluoxetine enantiomers. We aimed to evaluate whether exposure ...