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Electrical stimulation induces IL-6 in skeletal muscle through extracellular ATP by activating Ca2+ signals and an IL-6 autocrine loop
(American Physiological Society, 2014)
Interleukin-6 (IL-6) is an important myokine that is highly expressed in skeletal muscle cells upon exercise. We assessed IL-6 expression in response to electrical stimulation (ES) or extracellular ATP as a known mediator ...
Purinergic Signaling Controls Spontaneous Activity in the Auditory System throughout Early Development
(Society for Neuroscience, 2021-01)
Spontaneous bursts of electrical activity in the developing auditory system arise within the cochlea before hearing onset and propagate through future sound-processing circuits of the brain to promote maturation of auditory ...
Neuroglia and their roles in central respiratory control; an overview
(Elsevier B. V., 2015)
While once viewed as mere housekeepers, providing structural and metabolic support for neurons, it is now clear that neuroglia do much more. Phylogenetically, they have undergone enormous proliferation and diversification ...
Extrinsic Purinergic Regulation of Neural Stem/Progenitor Cells: Implications for CNS Development and Repair
(HUMANA PRESS INCTOTOWA, 2013-08-02)
There has been tremendous progress in understanding neural stem cell (NSC) biology, with genetic and cell biological methods identifying sequential gene expression and molecular interactions guiding NSC specification into ...
Purinergic receptor stimulation induces calcium oscillations and smooth muscle contraction in small pulmonary veins
(Wiley, 2018-07)
The small pulmonary veins (SPVs) may play a role in the development of pulmonary hypertension and pulmonary oedema via active changes in SPV diameter, mediated by vascular smooth muscle cell (VSMC) contraction. However, ...
Regulation of ventral surface CO2/H+-sensitive neurons by purinergic signalling
(WILEY-BLACKWELLMALDEN, 2012)
Central chemoreception is the mechanism by which the brain regulates breathing in response to changes in tissue CO2/H+. Abrainstemregion called the retrotrapezoid nucleus (RTN) contains a population of CO2/H+-sensitive ...