Now showing items 11-20 of 2423
Collective variable driven molecular dynamics to improve protein protein docking scoring
In biophysics, the structural prediction of protein–protein complexes starting from the unbound form of the two interacting monomers is a major difficulty. Although current computational docking protocols are able to ...
The Protein Interactome Of Collapsin Response Mediator Protein-2 (crmp2/dpysl2) Reveals Novel Partner Proteins In Brain Tissue
(WILEY-V C H VERLAG GMBHWEINHEIM, 2015)
H-bond refinement for electron transfer membrane-bound protein-protein complexes: cytochrome c oxidase and cytochrome c552
In this study we propose a protocol to evaluate membrane-bound cytochrome c oxidase–cytochrome c552 docking candidates. An initial rigid docking algorithm generates docking poses of the cytochrome c oxidase–cytochrome c552, ...
Integrative meta-analysis identifies microRNA-regulated networks in infantile hemangioma
Background: Hemangioma is a common benign tumor in the childhood; however our knowledge about the molecular mechanisms of hemangioma development and progression are still limited. Currently, microRNAs (miRNAs) have been ...
Evidence for the interaction of the regulatory protein Ki-1/57 with p53 and its interacting proteins
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2006)
The fragility of protein-protein interaction networks
The capacity to resist perturbations from the environment is crucial to the survival of all organisms. We quantitatively analyze the susceptibility of protein interaction networks of numerous organisms to random and targeted ...
The role of protein disorder in the 14-3-3 interaction network
(Royal Society of Chemistry, 2012-11)
Disordered regions are segments of a protein that do not fold completely and thus remain flexible. These regions have key physiological roles, particularly in phospho-proteins, which are enriched in disorder-promoting ...