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Effects of parboiled rice diet on oxidative stress parameters in kidney of rats with streptozotocin-induced diabetes
(Mary Ann Liebert, 2012-07)
The effect of parboiled rice (PR) and white rice (WR) diets on oxidative stress (OS) parameters was investigated in the kidneys of rats with streptozotocin-induced diabetes (40mg kg-1, iv). The experimental groups (n=8) ...
N -Acetyl- l -Cysteine treatment efficiently prevented pre-diabetes and inflamed-dysmetabolic liver development in hypothalamic obese rats
(Pergamon-Elsevier Science Ltd, 2018-04)
AimHypothalamic obese rats are characterized by pre-diabetes, dyslipidemia, hyperadiposity, inflammation and, liver dysmetabolism with oxidative stress (OS), among others. We studied endocrine-metabolic dysfunctions and, ...
Cacao extract enriched in polyphenols prevents endocrine-metabolic disturbances in a rat model of prediabetes triggered by a sucrose rich diet
(Elsevier, 2020-01)
Ethnopharmacological relevance: Cocoa extracts rich in polyphenols are used as potential agent for treating diabetes. Cocoa polyphenols have been proved to ameliorate important hallmarks of type-2 diabetes (T2D). They can ...
Antigen-based nano-immunotherapy controls parasite persistence, inflammatory and oxidative stress, and cardiac fibrosis, the hallmarks of chronic chagas cardiomyopathy, in a mouse model of trypanosoma cruzi infection
(Multidisciplinary Digital Publishing Institute, 2020-02-21)
Chagas cardiomyopathy is caused by Trypanosoma cruzi (Tc). We identified two candidate antigens (TcG2 and TcG4) that elicit antibodies and T cell responses in naturally infected diverse hosts. In this study, we cloned TcG2 ...
Capacitation-induced mitochondrial activity Is required for sperm fertilizing ability in mice by modulating hyperactivation
(Frontiers Media, 2021-10)
To become fully competent to fertilize an egg, mammalian sperm undergo a series of functional changes within the female tract, known as capacitation, that require an adequate supply and management of energy. However, the ...
Urban air pollution induces alterations in redox metabolism and mitochondrial dysfunction in mice brain cortex
(Elsevier Science Inc., 2021-06-15)
Previous reports indicate that the central nervous system (CNS) is a target of airpollution, causing tissue damage and functional alterations. Oxidative stress andneuroinflammation have been pointed out as possible mechanisms ...
Liver preconditioning induced by iron in a rat model of ischemia/reperfusion
(Pergamon-Elsevier Science Ltd, 2011-08)
Aims: Liver preconditioning against ischemia-reperfusion (IR) injury is a major area of experimental research, in which regulation of gene expression with cytoprotective responses due to transient oxidative stress development ...
Methylmercury-induced developmental toxicity is associated with oxidative stress and cofilin phosphorylation. Cellular and human studies
(Elsevier Science, 2017-03)
Environmental exposure to methylmercury (MeHg) during development is of concern because it is easily incorporated in children's body both pre- and post-natal, it acts at several levels of neural pathways (mitochondria, ...
Catechin and quercetin attenuate adipose inflammation in fructose-fed rats and 3T3-L1 adipocytes
(Wiley VCH Verlag, 2015-01-24)
Scope: This study evaluated the capacity of dietary catechin (C), quercetin (Q), and the combination of both (CQ), to attenuate adipose inflammation triggered by high fructose (HFr) consumption in rats and by tumor necrosis ...