Buscar
Mostrando ítems 31-40 de 87
Mechanochemical disulfide reduction reveals imprints of noncovalent sulfur⋯oxygen chalcogen bonds in protein-inspired mimics in aqueous solution
(Royal Society of Chemistry, 2020-11)
The surprisingly rich chemistry of mechanically activated cleavage of disulfide bonds has been uncovered only recently. Using a disulfide protein mimic together with Cleland's reagent (DTT) as the attacking nucleophile in ...
Spectroscopic and Theoretical Study of CuI Binding to His111 in the Human Prion Protein Fragment 106-115
(American Chemical Society, 2016-03)
The ability of the cellular prion protein (PrPC) to bind copper in vivo points to a physiological role for PrPC in copper transport. Six copper binding sites have been identified in the nonstructured N-terminal region of ...
Diet with isolated soy protein reduces oxidative stress and preserves ventricular function in rats with myocardial infarction
(Elsevier, 2009-02)
We investigated the effects of an isolated soy protein (ISP) diet offered over a 9-week period to rats in whom myocardial infarction (MI) had been induced, and a casein diet given as a control. Male Wistar rats were assigned ...
Early loss of cardiac function in acute myocardial infarction is associated with redox imbalance
(Pulsus Group Inc, 2012-12)
BACKGROUND: The loss of viable myocardium subsequent to myocardial infarction (MI) impairs cardiac function, and oxidative stress is considered to be critical in this process. OBJECTIVES: To assess cardiac function and ...
Interaction of gabaergic ketones with model membranes: A molecular dynamics and experimental approach
(Elsevier Science, 2018-08)
γ-Aminobutyric-acid receptor (GABA A -R), a membrane intrinsic protein, is activated by GABA and modulated by a wide variety of recognized drugs. GABA A -R is also target for several insecticides which act by recognition ...
Protein-cofactor interactions in bacterial reaction centers from Rhodobacter sphaeroides R-26: I. Identification of the ENDOR lines associated with the hydrogen bonds to the primary quinone QA-
(Cell Press, 2006-12)
Hydrogen bonds are important in determining the structure and function of biomolecules. Of particular interest are hydrogen bonds to quinones, which play an important role in the bioenergetics of respiration and photosynthesis. ...
Deleterious effects induced by oxidative stress in liver nuclei from rats receiving an alcohol-containing liquid diet
(Sage Publications Ltd, 2008-11)
Highly purified rat-liver nuclei were previously shown to have nuclear ethanol (EtOH) metabolizing system able to bioactivate alcohol to acetaldehyde and 1-hydroxyethyl radicals. These reactive metabolites were able to ...
Valproic acid has neuroprotective effect in an acute model of oxidative stress in ratsEl ácido valproico tiene efecto neuroprotector en un modelo de estrés oxidativo agudo en ratas
(Universidad Centroccidental Lisandro Alvarado, 2015)
Germinability and antioxidant metabolism in Passiflora caerulea L. seeds exposed to salt stressGerminabilidad y metabolismo antioxidante en semillas de Passiflora caerulea L. expuestas a estrés salino
(Museo Argentino de Ciencias Naturales Bernardino Rivadavia, 2018-06)
P. caerulea es la especie Passiflora con más amplia distribución en Argentina. Si bien es necesario implementar prácticas de cultivo para disminuir el impacto debido a su extracción indiscriminada, la información sobre ...
Endometriosis progression in tumor necrosis factor receptor p55-deficient mice: Impact on oxidative/nitrosative stress and metallomic profile
(Elsevier Gmbh, 2019-03)
The present study was conducted to investigate whether the deficiency of tumor necrosis factor receptor p55 (TNFRp55) modulates oxidative/nitrosative stress and metallomic profile into the peritoneal cavity during the ...