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Role of complement C5a in mechanical inflammatory hypernociceptio: potential use of C5a receptor antagonists to control inflammatory pain
(NATURE PUBLISHING GROUP, 2008)
particularly neutrophil chemoattraction. Herein, the role of C5a in the genesis of inflammatory hypernociception was investigated in rats and mice using the specific C5a receptor antagonist PMX53 (AcF-[OP(D-Cha)WR]). ...
Chronic Alcohol Consumption Alters Periodontal Health in Rats
(Wiley, 2014-06)
BACKGROUND: The aim of this study was to assess the effects of chronic alcohol consumption on periodontitis development in rats.
METHODS: Periodontal disease was experimentally induced by lipopolysaccharide (LPS; 2 mg/ml) ...
Plant derived alkaloid (-)-cassine induces anti-inflammatory and anti-hyperalgesics effects in both acute and chronic inflammatory and neuropathic pain models
(Pergamon-Elsevier B.V. Ltd, 2012-02-01)
Natural products have been revealed as relevant sources of therapeutic agents including those for the management of pain states. In this study, the anti-nociceptive and anti-inflammatory effects of (-)-cassine, isolated ...
Effects of dominant follicle aspiration and treatment with recombinant bovine somatotropin (BST) on ovarian follicular development in Nelore (Bos indicus) heifers
(Elsevier B.V., 2000-08-01)
Follicle ablation has been recognized as an efficient method of follicular wave synchronization. Treatment with recombinant bovine somatotropin (BST) has been shown to enhance follicular development in <(Bos taurus)under ...
Downregulation of nuclear factor-kappa B (NF-kappa B) pathway by silibinin in human monocytes challenged with Paracoccidioides brasiliensis
(Pergamon-Elsevier B.V. Ltd, 2010-06-05)
Aims: Silibinin is the major active component of silymarin, a polyphenolic plant flavonoid that has anti-inflammatory effects. The modulatory effect of silibinin on monocyte function against Paracoccidioides brasiliensis ...
Mechanisms Involved in the Antinociceptive Effects of 7-Hydroxycoumarin
(2011)
7-Hydroxycoumarin (umbelliferone, 1), the main metabolite of coumarin,
has been reported to produce potent antinociceptive effects in animal models of pain.
However, the biochemical events involved in antinociception ...
Expression of fibroblast growth factor 22 (FGF22) and its receptor, FGFR1B, during development and regression of bovine corpus luteum
(Elsevier B.V., 2019-02-01)
The aim of this study was to determine the expression of fibroblast growth factor 22 (FGF22) in the bovine corpus luteum (CL) and to investigate the effects of in vivo total or partial cloprostenol-induced luteolysis on ...
Effect of low-level laser therapy as an adjuvant in the treatment of periodontitis induced in rats subjected to 5-fluorouracil chemotherapy
(2016-10-01)
Background and Objective: This study aimed to assess the effect of multiple sessions of a low-level laser therapy (LLLT) adjuvant to scaling and root planing (SRP) on the treatment of experimental periodontitis (EP) in ...
Ovarian superstimulatory response and embryo production in mares treated with equine pituitary extract twice daily
(Elsevier B.V., 2001-09-15)
Equine pituitary extract (EPE), has been reported to induce multiple ovulation in mares, however ovulation rates are poor in comparison to those obtained in other species. Attempts to improve the effectiveness of EPE for ...
Virtual screening of plants extracts with anti-chagasic activity guided by Omics data
(Asociación Argentina de Bioinformática y Biología Computacional, 2021)
Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and their treatment consists in the use of two nitro heterocyclic compounds that both present high toxicity and low effectiveness during the chronic ...