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Influence of chitosan-tripolyphosphate nanoparticles on thermosensitive polymeric hydrogels: structural organization, drug release mechanisms and cytotoxicity
(Taylor & Francis As, 2019-04-04)
Chitosan-tripolyphosphate (CS-TPP) nanoparticles containing naproxen (NPX) were dispersed in poloxamer (PL) as unique (PL407) or binary (PL407-PL403) systems. Nanoparticles presented diameter of similar to 250 nm and zeta ...
The role of stabilizers and mechanical processes on physico-chemical and anti-inflammatory properties of methotrexate nanosuspensions
(2020-06-01)
The aim of this study was to investigate two different mechanical processes (Ultra-turrax® and Sonication) and two stabilizers (Methyl cellulose (MC) and Poloxamer 407 (P407)) on the physico-chemical and anti-inflammatory ...
Albendazole solid dispersions against alveolar echinococcosis: a pharmacotechnical strategy to improve the efficacy of the drug
(Cambridge University Press, 2020-04)
Alveolar echinococcosis is a neglected parasitic zoonosis caused by Echinococcus multilocularis. The pharmacological treatment is based on albendazole (ABZ). However, the low water solubility of the drug produces a limited ...
Development and in vitro evaluation of solid dispersions as strategy to improve albendazole biopharmaceutical behavior
(Future Medicine Ltd., 2018-09)
Solid dispersions using Poloxamer 407 as carrier were developed to improvealbendazole (ABZ) solubility and dissolution profiles. ABZ/poloxamer solid dispersions were prepared, and dissolution profiles were mathematically ...
Formulação de gel termossensível mucoadesivo contendo cloridrato de pilocarpina para tratamento de xerostomia
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Ciencias Farmaceuticas, 2018)
Comparison Of The Properties Of Membranes Produced With Alginate And Chitosan From Mushroom And From Shrimp
(Elsevier Science BVAmsterdam, 2016)
Development of thermoresponsive ibuprofen nanoemulsion based-gel for potential topical use
(Universidade Federal do Rio Grande do NorteBrasilUFRNFarmácia, 2019)
Inhibitory Effect of a KSL-W Peptide-Loaded Poloxamer 407-Based Microemulsions for Buccal Delivery on Fusobacterium nucleatum Biofilm
(Amer Scientific Publishers, 2020-03-01)
KSL-W peptide has demonstrated antibacterial and antifungal activity and inhibitory effects against oral biofilm. This study aimed to check out the effect of chlorhexidine (CLX) or KSL-W peptide-loaded poloxamer 407-based ...
Third-generation solid dispersion combining Soluplus and poloxamer 407 enhances the oral bioavailability of resveratrol
(Elsevier B.V., 2021-02-15)
Resveratrol is a very promising anti-oxidant drug candidate with low oral bioavailability due to its intrinsic poor water solubility, intestinal efflux and metabolization mechanisms. Resveratrol solubility high-throughput ...