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Avaliação do processo de reparo alveolar em ratos pinealectomizados utilizando fluorocromos
(Universidade Estadual Paulista (Unesp), 2009-09)
Studies show that people who work at night shift lose the ability to circadian release of melatonin (Me) by the pineal gland, because this hormone is only released by this gland under conditions of darkness and during ...
Melatonina e o tecido adiposo marrom em machos adultos
(Universidade Federal de São Paulo (UNIFESP), 2018-11-29)
Aim: Evaluate the role of melatonin in the metabolism of brown adipose tissue (BAT)
in male adult rats. Methods: Wistar rats (8 weeks) were assigned to three groups:
Control, Pinealectomized (PINX) and Pinealectomized ...
Melatonin suppression increases the incidence and progression of chemically induced oral cancer in rats
(Universidade Estadual Paulista (Unesp), 2019-08-26)
Estudos sugerem que a supressão de melatonina e disfunção circadiana em trabalhadores noturnos podem estar relacionadas ao desenvolvimento e à progressão do câncer. Pesquisas têm mostrado também que a incidência tumoral ...
Daily melatonin administration improves osseointegration in pinealectomized rats
(Univ Sao Paulo Fac Odontologia Bauru, 2018-01-01)
The hypothesis of this study was that the peri-implant bone healing of the group of pinealectomized rats would differ from the control group. The samples were subjected to immunohistochemical, microtomographic (total ...
Is melatonin deficiency a unifying pathomechanism of high risk patients with COVID-19?
An article by Zhang et al. [1] published in the March issue of Life
Sciences suggested melatonin as a potential adjuvant treatment for
COVID-19. Besides the antioxidative and immunomodulatory actions of
melatonin, there ...
Absence of Melatonin Induces Night-Time Hepatic Insulin Resistance and Increased Gluconeogenesis Due to Stimulation of Nocturnal Unfolded Protein Response
(ENDOCRINE SOC, 2011)
It is known that the circadian rhythm in hepatic phosphoenolpyruvate carboxykinase expression (a limiting catalytic step of gluconeogenesis) and hepatic glucose production is maintained by both daily oscillation in autonomic ...
Maternal Melatonin Programs the Daily Pattern of Energy Metabolism in Adult Offspring
(PUBLIC LIBRARY SCIENCESAN FRANCISCO, 2012)
Background: Shift work was recently described as a factor that increases the risk of Type 2 diabetes mellitus. In addition, rats born to mothers subjected to a phase shift throughout pregnancy are glucose intolerant. ...
Malaria: Therapeutic implications of melatonin
(Wiley Blackwell Publishing, Inc, 2010-01)
Malaria, which infects more than 300 million people annually, is a serious disease. Epidemiological surveys indicate that of those who are affected, malaria will claim the lives of more than one million individuals, mostly ...
Malaria : therapeutic implications of melatonin
(Wiley, 2010)
Abstract: Malaria, which infects more than 300 million people annually, is a serious disease. Epidemiological surveys indicate that of those who are affected, malaria will claim the lives of more than one million individuals, ...
Melatonin promotes reduction in TNF levels and improves the lipid profile and insulin sensitivity in pinealectomized rats with periodontal disease
(2018-11-15)
Aim: This study aimed to investigate the effects of melatonin (ME) on insulin resistance (IR) and signaling (IS), proinflammatory cytokine levels, and lipid profiles in pinealectomyzed (PNX) rats with periodontal disease ...