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Inflammatory events during murine squamous cell carcinoma development
(2012-11-23)
Abstract
Background
Squamous cell carcinoma (SCC) is one of the most common human cancers worldwide. In SCC, tumour development is accompanied by an immune response that leads ...
Plumage variation in the Planalto Woodcreeper (Dendrocolaptes platyrostris) and the melanocortin-1 receptor gene (MC1R)
(Soc Brasileira Ornitologia, 2013-03)
The Planalto Woodcreeper (Dendrocolaptes platyrostris) presents “pale” and “dark” plumage variants, which are distributed throughout the Cerrado and Caatinga, and throughout the Atlantic Forest, respectively. To understand ...
Towards the resolution of a long-standing evolutionary question: muscle identity and attachments are mainly related to topological position and not to primordium or homeotic identity of digits
(Wiley, 2015-04)
Signaling for limb bone development usually precedes that for muscle development, such that cartilage is generally present before muscle formation. It remains obscure, however, if: (i) tetrapods share a general, predictable ...
Análise do padrão de atividade e ecologia térmica do lagarto Tropidurus torquatus no sul do Brasil
(Universidade Federal de Santa MariaBrasilUFSMCentro de Ciências Naturais e Exatas, 2012-07-31)
Lizards are model organisms in ecology, providing understanding of patterns and relationships
between organisms and their environment. Tropidurus torquatus is a species with populations
living in different habitats and ...
Altered cardiomyocyte function and trypanosoma cruzi persistence in chagas disease
(Wiley-Blackwell, 2016)
Chagas disease, caused by the triatominae Trypanosoma cruzi, is one of the leading causes of heart malfunctioning in Latin America. The cardiac phenotype is observed in 20-30% of infected people 10-40 years after their ...
Is age a risk factor for liver disease and metabolic alterations in ataxia Telangiectasia patients?
(Biomed Central Ltd, 2017)
Background: Ataxia telangiectasia (A-T) is a neurodegenerative disease that leads to mitochondrial dysfunction and oxidative stress. Insulin resistance (IR), type 2 diabetes and the risk for development of cardiovascular ...
Implicações da capacidade de combinação e da distância genética na seleção de genitores de trigo (Triticum aestivum L.)
(Universidade Tecnológica Federal do ParanáPato BrancoPrograma de Pós-Graduação em Agronomia, 2010)
The identification of efficient methodologies for the choice of parents in breeding programs has received great attention from researchers. The diallel cross is widely used with this purpose, however, as the number of ...
Adaptabilidade e estabilidade de genótipos de feijão em Dois Vizinhos - PR
(Universidade Tecnológica Federal do ParanáDois VizinhosBrasilAgronomiaUTFPR, 2016-12-07)
Bean (Phaseolus vulgaris) is one of the most widely grown legume species in the world due to its nutritional properties. Brazil is currently the third largest producer of beans, with an average annual production of 2.5 ...
Concordance of CCR5 genotypes that influence cell-mediated immunity and HIV-1 disease progression rates
We used cutaneous delayed-type hypersensitivity responses, a powerful in vivo measure of cell-mediated immunity, to evaluate the relationships among cell-mediated immunity, AIDS, and polymorphisms in CCR5, the HIV-1 ...
GRAIL and Otubain-1 are Related to T Cell Hyporesponsiveness during Trypanosoma cruzi Infection
(Public Library of Science, 2017-01)
Trypanosoma cruzi infection is associated with severe T cell unresponsiveness to antigens and mitogens and is characterized by decreased IL-2 synthesis. In addition, the acquisition of the anergic phenotype is correlated ...