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Inducible nitric oxide synthase-deficient mice show exacerbated inflammatory process and high production of both Th1 and Th2 cytokines during paracoccidioidomycosis
(ELSEVIER SCIENCE BV, 2009)
Paracoccidioidomycosis, the major systemic mycosis in Latin America, is caused by fungus Paracoccidioides brasiliensis. To analyze the influence of inducible nitric oxide synthase (iNOS) in this disease, iNOS-deficient ...
Attempts at a peptide vaccine against paracoccidioidomycosis, adjuvant to chemotherapy
(SPRINGER, 2008)
Chemotherapy is the basis of treatment of paracoccidioidomycosis in its various forms. Depending on the Paracoccidioides brasiliensis virulence, the status of host immunity, the degree of tissue involvement and fungal ...
In Vitro Antifungal Activity and Toxicity of Itraconazole in DMSA-PLGA Nanoparticles
(AMER SCIENTIFIC PUBLISHERS, 2011)
Itraconazole (ITZ) is a drug used to treat various fungal infections and may cause side effects. The aim of this study was to develop and evaluate the in vitro activity of DMSA-PLGA nanoparticles loaded with ITZ against ...
Canine paracoccidioidomycosis: a seroepidemiologic study
(B I O S Scientific Publishers Ltd, 2001-06-01)
Sera from 305 dogs were analyzed by enzyme-linked immunosorbent assay (ELISA) to determine presence of the antibody anti-gp43, which reacts to a specific antigen of Paracoccidioides brasiliensis. the dogs were divided into ...
Characterization of monoclonal antibody MEST-2 specific to glucosylceramide of fungi and plants
(Oxford Univ Press Inc, 2001-02-01)
An IgG2a monoclonal antibody anti-glucosylceramide was established and termed MEST-2. High performance thin layer chromatography immunostaining, and solid-phase radioimmunoassay showed that MEST-2 reacts with glucosylceramide ...
Zoonotic parasites infecting free-living armadillos from Brazil
(2021-05-01)
Armadillos are specialist diggers and their burrows are used to find food, seek shelter and protect their pups. These burrows can also be shared with dozens of vertebrate and invertebrate species and; consequently, their ...
Atividade fungicida de células dendríticas humanas contra o Paracoccidioides brasiliensis: papel dos metabólitos do oxigênio, citocinas e receptores de reconhecimento padrãoFungicidal activity of dendritic cells against Paracoccidioides brasiliensis: role of oxygen metabolites, cytokines and pattern recognition receptors
(Universidade Estadual Paulista (Unesp), 2016)
Genotipagem do Paracoccidioides brasiliensis de diferentes amostras de pacientes atendidos no Hospital das Clínicas da Faculdade de Medicina de Botucatu
(Universidade Estadual Paulista (Unesp), 2018-02-27)
A paracoccidioidomicose é uma micose granulomatosa sistêmica, prevalente na América Latina, e que até recentemente acreditava-se ser causada apenas por uma espécie de fungo, o Paracoccidioides brasiliensis (P. brasiliensis). ...