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Purinergic signaling as alternative pathway to treat adult pulmonary arterial hypertension.
(2016)
INTRODUCTION: For a long time, the vasoactivity of pulmonary veins has been debated. Increasing evidences about the role of pulmonary veins to the total pulmonary vascular resistance has been particularly well supported ...
Purinergic-dependent contraction of small intrapulmonary veins: role in a pulmonary arterial hypertension rat model
(2016)
Abstract Body : Background: For a long time, the vasoactivity of pulmonary veins has been debated. Increasing
evidences about the role of pulmonary veins to the total pulmonary vascular resistance has been particularly ...
Pulmonary artery sarcoma and chronic thromboembolism
(ELSEVIER GMBH, URBAN & FISCHER VERLAG, 2008)
Pulmonary artery sarcoma is a rare and highly lethal disease whose clinical findings are often indistinguishable from those of chronic thromboembolic pulmonary hypertension. Partial improvement after thrombolytic therapy ...
Survival of patients with pulmonary arterial hypertension after the advent of specific pulmonary vasodilator therapies
(Soc. Médica Santiago, 2016)
Background: Pulmonary arterial hypertension (PAH) is a rare and progressive disease. Long-term survival remains poor despite of advances in specific vasodilator therapy. Aim: To describe the survival rate in a cohort of ...
Pulmonary Hypertension in Obese Mice Is Accompanied by a Reduction in PPAR-γ Expression in Pulmonary Artery
(2021-09-06)
Obesity and insulin resistance (IR) are well-studied risk factors for systemic cardiovascular disease, but their impact on pulmonary hypertension (PH) is not well clarified. This study aims to investigate if diet-induced ...
Long-term exposure to high-altitude chronic hypoxia during gestation induces neonatal pulmonary hypertension at sea level
(2010)
We determined whether postnatal pulmonary hypertension induced by 70% of pregnancy at high altitude (HA) persists once the offspring return to sea level and investigated pulmonary vascular mechanisms operating under these ...