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p75NTR and its ligand proNGF activate paracrine mechanisms etiological to the vascular, inflammatory, and neurodegenerative pathologies of diabetic retinopathy
(Society for Neuroscience, 2016-08)
In many diseases, expression and ligand-dependent activity of the p75NTR receptor can promote pericyte and vascular dysfunction, inflammation, glial activation, and neurodegeneration. Diabetic retinopathy (DR) is characterized ...
Alterações morfológicas nos vasos da íris de ratos normais e diabéticos aloxânicos
(Universidade Estadual Paulista (UNESP), 2014)
Could donor multipotent mesenchymal stromal cells prevent or delay the onset of diabetic retinopathy?
(Wiley, 2014)
Diabetes mellitus is a complex metabolic disease that has become a global epidemic with more than 285 million cases worldwide. Major medical advances over the past decades have substantially improved its management, extending ...
Proliferative retinopathy and neovascularization of the anterior segment in female type 2 diabetic rats
(BioMed Central, 2013-11)
Background: To examine the presence of diabetic retinopathy in a female rat model of type 2 diabetes fed on a high-fat diet (HFD). Methods: Wistar rats were injected with streptozotocin (STZ) at the age of two days and fed ...
Retinal upregulation of inflammatory and proangiogenic markers in a model of neonatal diabetic rats fed on a high-fat-diet
(BioMed Central, 2013-04)
Background: The contemporary peak of diabetes seems to be related to obesity, sedentary lifestyle and diet. Diabetic retinopathy is the most leading cause of blindness in adulthood in industrialized countries. Our purpose ...
Ultrastructural and morphometric aspects of ageing in the retinal capillaries of rats
(1997-04-01)
Age-related morphological, ultrastructural and morphometric changes in the capillaries of the superficial and deep plexuses of the rat retina were studied in animals aged from 3 to 15 months. Our results suggest that ...
Ultrastructural and morphometric aspects of ageing in the retinal capillaries of rats
(1997-04-01)
Age-related morphological, ultrastructural and morphometric changes in the capillaries of the superficial and deep plexuses of the rat retina were studied in animals aged from 3 to 15 months. Our results suggest that ...
Severe compromise of preosteoblasts in a surgical mouse model of bisphosphonate-associated osteonecrosis of the jaw
(2016)
Objectives: The effect of amino-bisphosphonates on osteoblastic lineage and its potential contribution to the pathogenesis of bisphosphonate-associated osteonecrosis of the jaw (BONJ) remain controversial. We assessed the ...
Could donor multipotent mesenchymal stromal cells prevent or delay the onset of diabetic retinopathy?
(Wiley, 2014)
Diabetes mellitus is a complex metabolic disease that has become a global epidemic with more than 285 million cases worldwide. Major medical advances over the past decades have substantially improved its management, extending ...
Solitary Fibrous Tumor/Hemangiopericytoma of the Ovary: A Rare Case Report and Literature Review.
(Academia Nacional de Medicina venezolana., 2022)