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Now showing items 31-40 of 1998
ATP and UTP stimulate bone morphogenetic protein-2,-4 and -5 gene expression and mineralization by rat primary osteoblasts involving PI3K/AKT pathway
(Elsevier Inc, 2013-08)
The modulation of purinergic receptors plays an important role in the regulation of bone formation by the osteoblast. On the other hand, bone morphogenetic proteins (BMPs), members of the transforming growth factor-β ...
Morphological changes induced by advanced glycation endproducts in osteoblastic cells: Effects of co-incubation with alendronate
(Elsevier, 2013-09)
Advanced glycation endproducts (AGEs) accumulate with age in various tissues, and are further increased in patients with Diabetes mellitus, in which they are believed to contribute to the development and progression of ...
Brucella abortus invasion of osteoblasts inhibits bone formation
(American Society for Microbiology, 2012-06-12)
Osteoarticular brucellosis is the most common presentation of the active disease in humans. Loss of bone is a serious complication of localized bacterial infection of bones or the adjacent tissue, and brucellosis proved ...
Mll-COMPASS complexes mediate H3K4me3 enrichment and transcription of the osteoblast master gene Runx2/p57 in osteoblasts
(Facultad de Medicina y Ciencia, 2019)
Expression of Runx2/p57 is a hallmark of the osteoblast-lineage identity. Although several regulators that control the expression of Runx2/p57 during osteoblast-lineage commitment have been identified, the epigenetic ...
First insight on the impact of an osteoblastic layer on the bio-tribocorrosion performance of Ti6Al4V hip implants
(Elsevier B.V., 2015-01-15)
In uncemented Ti6Al4V hip implants, the bone-stem interface is subjected to cyclic loading motion driven by the daily activities of the patients, which may lead to the complete failure of the implant in the long term. It ...
Aging impairs osteoblast differentiation of mesenchymal stem cells grown on titanium by favoring adipogenesis
(Univ Sao Paulo Fac Odontologia Bauru, 2016-07-01)
Aging negatively affects bone/titanium implant interactions. Our hypothesis is that the unbalance between osteogenesis and adipogenesis induced by aging may be involved in this phenomenon. Objective: We investigated the ...
Aging impairs osteoblast differentiation of mesenchymal stem cells grown on titanium by favoring adipogenesis
(2016-07-01)
Aging negatively affects bone/titanium implant interactions. Our hypothesis is that the unbalance between osteogenesis and adipogenesis induced by aging may be involved in this phenomenon. Objective: We investigated the ...
Dose- and time-dependent effects of taxifolin on viability and mineralization markers of osteoblast-like cells
(2021-01-01)
The current study evaluated the effects of taxifolin treatments on the viability of osteoblast-like cells, and on the expression of early mineralization markers, as part of the ongoing search for new endodontic materials ...
Titanium-enriched medium drives low profile of ECM remodeling as a pre-requisite to pre-osteoblast viability and proliferative phenotype
(2018-12-01)
Titanium is widely used for biomedical applications, but little information is being delivered regarding the cellular/molecular mechanisms explaining their efficacy, mainly considering the effects of the Ti-released trace ...