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Analysis of the opioid–opioid combinations according to the nociceptive stimulus in mice
(ELSEVIER, 2010)
The purpose of the present study was to characterize the antinociceptive effects of tramadol, fentanyl and
morphine,whentwoofthemwere systemically combined in a 1:1 potency ratio, in the hot plate, the acetic
acid writhing, ...
Analysis of the opioid-opioid combinations according to the nociceptive stimulus in mice
(2010)
The purpose of the present study was to characterize the antinociceptive effects of tramadol, fentanyl and morphine, when two of them were systemically combined in a 1:1 potency ratio, in the hot plate, the acetic acid ...
Isobolographic analysis of the opioid-opioid interactions in a tonic and a phasic mouse model of induced nociceptive pain
(BioMed Central, 2014)
Background: Opioids have been used for the management of pain and coadministration of two opioids may
induce synergism. In a model of tonic pain, the acetic acid writhing test and in a phasic model, the hot plate, ...
Improving the availability and accessibility of opioids for the treatment of pain: the International Pain Policy Fellowship
(Care in Cancer, 2011-05-24)
Opioid analgesics are simultaneously indispensable
medicines for the treatment of moderate to severe pain
and are harmful when abused. The challenge for governments
is to balance the obligation to prevent diversion,
trafficking, ...
Patrones de prescripción de opioides en Colombia
(Especialización en medicina del dolor y cuidados paliativosUniversidad El BosqueFacultad de Medicina, 2021)
Los analgésicos opioides han demostrado ser una intervención efectiva en el control del dolor que no está desprovistos de riesgos. Con la declaración de la epidemia mundial de opioides se hizo clara la necesidad de vigilar ...
Usos terapeuticos potenciales de los antagonistas opioides: Fisiopatologia y evidencia preclinica
Opioid system, which involved endogenous opioid peptides and their receptors (Miu, Kappa, delta and ORL), has a main role in the physiology of several systems. At the same time, there is cumulating evidence in the role of ...
General Practitioners' Barriers and Facilitators to Opioid Prescription in Medellin, Colombia (S810)
Objectives 1. Identify the attitudes and specific practices of general practitioners regarding opioid prescription. 2. Recognize general practitioners’ perceived barriers and facilitators of opioid prescription. 3. Describe ...
Spread the Word: There Are Two Opioid Crises!
(2020-08-01)
Pain is associated with emotional and physical suffering that severely impacts quality of life. Many guidelines for the treatment of moderate to severe cancer pain indicate the use of opioids. For a small proportion of the ...
Improving availability of and access to opioids in Colombia: Description and preliminary results of an action plan for the country
(Journal of Pain and Symptom Management, 2009-04-01)
Latin America consumes less than 2.7% of the morphine in the world, as reported by the governments to the International Narcotics Control Board. Methods to improve access to opioids for the treatment of pain have been ...