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Late Breaking Abstract - Effects of preventive exercise in monocrotaline rat model with pulmonary hypertension
(European Respiratory Soc Journals Ltd, 2019-09-28)
Low doses of monocrotaline in rats cause diminished bone marrow cellularity and compromised nitric oxide production by peritoneal macrophages
(INFORMA HEALTHCARE, 2009)
Monocrotaline (MCT) is a pyrrolizidine alkaloid found in a variety of plants. The main symptoms of MCT toxicosis in livestock are related to hepato- and nephrotoxicity; in rodents and humans, the induction of a pulmonary ...
The role of astrocytes in metabolism and neurotoxicity of the pyrrolizidine alkaloid monocrotaline, the main toxin of Crotalaria retusa
(2012)
The metabolic interactions and signaling between neurons and glial cells are necessary for the development and maintenance of brain functions and structures and for neuroprotection, which includes protection from chemical ...
Genotoxicity and morphological changes induced by the alkaloid monocrotaline, extracted from Crotalaria retusa, in a model of glial cells
(Elsevier, 2010-01)
Plants of Crotalaria genus (Leguminosae) present large amounts of the pyrrolizidine alkaloid monocrotaline (MCT) and cause intoxication to animals and humans. Therefore, we investigated the MCT-induced cytotoxicity, ...
Pyrrolizidine alkaloid toxicosis and hepatic encephalopathy in horses in Easter Island, Chile
(2018)
A group of horses died in Easter Island following anorexia, weight loss and neurological signs. Similar cases have occurred since the introduction of a plant containing pirrolizidine alkaloid to the island. This study ...
Experimental and theoretical studies on the characterization of monocrotaline by infrared and Raman spectroscopies
(Journal of Molecular Structure, 2018)