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Modulation of the activity of the transverse tubule Mg2+ATPase from frog skeletal muscle by a monoclonal antibody in vitro
(Kluwer Academic Publishers, 1991)
We have established several hybridoma lines that produce monoclonal antibodies against transverse tubule (t-tubule) proteins from frog skeletal muscle. The specificity of these antibodies was characterized by ELISA and ...
Biosimilar monoclonal antibodies in Latin America
(IntechOpen, 2021)
Antibodies, also known as immunoglobulins, are complex glycoproteins produced by B-cells against foreign substances as part of the adaptive immune response [1, 2]. The invention of the hybridoma technology in 1975 by Köhler ...
Multiple Tolerization Reduces Antibody Binding Against Tolerogen Cells: Implications for the Production of Monoclonal Antibodies
(2018-04-01)
We report an immunization technique that can update the production of monoclonal antibodies (mAbs): the multiple tolerization subtractive immunization (MTSI). A total of 10 BALB/C mice were used. Animals in group 1 received ...
Rapid and efficient immunization method using popliteal lymph nodes to generate monoclonal antibodies
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)
Anti-Acinetobacter baumannii monoclonal antibody as a potential immunological tool
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2019)
Enhanced immunization techniques to obtain highly specific monoclonal antibodies
(2018-01-02)
Despite fast advances in genomics and proteomics, monoclonal antibodies (mAbs) are still a valuable tool for areas such as the evolution of basic research in stem cells and cancer, for immunophenotyping cell populations, ...
Manufacturing of high-concentration monoclonal antibodies via an easy to handle disposable modular minifermenter.
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)