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Up-regulation of pro-angiogenic molecules and events does not relate with an angiogenic switch in metastatic osteosarcoma cells but to cell survival features
(Springer, 2021-05)
Osteosarcoma (OS) is the most frequent malignant bone tumor, affecting predominantly children. Metastases represent a major clinical challenge and an estimated 80% would present undetectable micrometastases at diagnosis. ...
Heparin receptors in two murine mammary adenocarcinomas with different metastatic ability: relationship with growth inhibition
(Elsevier, 1995-04-14)
Binding of heparin to primary cultured cells of two murine mammary adenocarcinomas with low (M3) and high (MM3) lung, metastatic capacity was determined. Heparin binding was rapid, specific and saturable. MM3 cells grown ...
Metastatic Cervical Carcinoma Of The Jaw Presenting As Periapical Disease
(Blackwell Publishing Ltd, 2015)
Progesterone receptor isoform ratio dictates antiprogestin/progestin effects on breast cancer growth and metastases: A role for NDRG1
(John Wiley & Sons Inc., 2021)
Progesterone receptors (PRs) ligands are being tested in luminal breast cancer. There are mainly two PR isoforms, PRA and PRB, and their ratio (PRA/PRB) may be predictive of antiprogestin response. Our aim was to investigate: ...
Low Oct4 expression in mesenchymal stem cells contributes to the development of the bone marrow pre-metastatic niche in advanced breast cancer patients
(Fundación Revista Medicina, 2021)
The imbalance between osteogenesis and osteoclastogenesis in the bone marrow (BM) microenvironment seems to play an essential role in the establishment of bone metastasis in untreated advanced breast cancer patients (BCP). ...
Modulation of fibronectin expression and proteolytic activity associated with the invasive and metastatic phenotype in two new murine mammary tumor cell lines
(Spandidos Publications, 1997)
Two cell lines obtained by sequential subcultures from primary cultures of the murine mammary adenocarcinomas M3 and MM3 were characterized. During LM3 cell line evolution an increase in the anchorage-independent growth ...
Isolation and characterization of murine mammary cell lines with differentiated aggressive phenotype
(Medicina (Buenos Aires), 2019)
Breast cancer is the first cause of death from female cancer. The recurrence of the disease originated at the level of secondary organs, or metastasis, is responsible for 90% of deaths from cancer. The factors that endow ...