Now showing items 31-40 of 157
Acute exercise induces a phenotypic switch in adipose tissue macrophage polarization in diet-induced obese rats
Involvement of TLR6 in the induction of COX-2, PGE2 and IL-10 in macrophages by lipids from virulent S2P and attenuated R1A Babesia bovis strains
(Elsevier Science, 2016-06)
Toll like receptors (TLRs) are involved in the modulation of diverse host genes expression through a complex network of signalling events that allow for an appropriate response to a microbial pathogen. In the present work ...
Stg fimbrial operon from S. Typhi STH2370 contributes to association and cell disruption of epithelial and macrophage-like cells
(Sociedad de Biología de Chile, 2015)
BACKGROUND: Salmonella enterica serovar Typhi (S. Typhi) stg operon, encoding a chaperone/usher fimbria (CU), contributes to an increased adherence to human epithelial cells. However, one report suggests that the presence ...
Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model
(Oncotarget eiditorial, 2016-02)
Chronic obesity and Chagas disease (caused by the protozoan Trypanosoma cruzi) represent serious public health concerns. The interrelation between parasite infection, adipose tissue, immune system and metabolism in an ...
Glucocorticoids impair phagocytosis and inflammatory response against crohn's disease-associated adherent-invasive escherichia coli
(Frontiers Media, 2018-05-16)
Crohn's disease (CD) is a chronic inflammatory bowel disorder characterized by deregulated inflammation triggered by environmental factors Notably, adherent-invasive Escherichia coli (AIEC), a bacterium with the ability ...
An in vitro method for studying subcellular rearrangements during cell polarization in Drosophila melanogaster hemocytes
(Elsevier Ireland Ltd, 2018)
© 2018Thanks to the power of Drosophila genetics, this animal model has been a precious tool for scientists to uncover key processes associated to innate immunity. The fly immune system relies on a population of macrophage-like ...
Eferocitose na presença de PAMP estimula ativação de macrófagos de perfil misto M1/M2
(Universidade Estadual Paulista (UNESP), 2015-05-15)
The phagocytosis of apoptotic cells is dynamic and crucial for homeostasis after injury. Macrophages act on the clearance of apoptotic cells and collaborate with defense against microorganisms. There are at least two ...
Brazilian Red Propolis Attenuates Inflammatory Signaling Cascade In Lps-activated Macrophages
(PUBLIC LIBRARY SCIENCESAN FRANCISCO, 2015)
IL-6 promotes M2 macrophage polarization by modulating purinergic signaling and regulates the lethal release of nitric oxide during Trypanosoma cruzi infection.
(Elsevier Science, 2017-04)
The production of nitric oxide (NO) is a key defense mechanism against intracellular pathogens but it must be tightly controlled in order to avoid excessive detrimental oxidative stress. In this study we described a novel ...
Eferocitose de células de carcinoma espinocelular de cabeça e pescoço por macrófagos: influência da galanina, dos produtos solúveis secretados por células tumorais e do fenótipo dos macrófagos
(Universidade Estadual Paulista (UNESP), 2018-03-28)
Os macrófagos representam uma das principais pontes entre imunidade inata e adaptativa e estão presentes em grande número tanto no estroma circundando tumores sólidos quanto no interior da massa tumoral (TAMs, tumor-associated ...