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New Perspectives to Improve Mesenchymal Stem Cell Therapies for Drug-Induced Liver Injury
(2022)
Abstract: Drug-induced liver injury (DILI) is one of the leading causes of acute liver injury. Many factors may contribute to the susceptibility of patients to this condition, making DILI a global medical problem that has ...
Administration of multipotent mesenchymal stromal cells restores liver regeneration and improves liver function in obese mice with hepatic steatosis after partial hepatectomy
(BioMed Central, 2017)
Background: The liver has the remarkable capacity to regenerate in order to compensate for lost or damaged
hepatic tissue. However, pre-existing pathological abnormalities, such as hepatic steatosis (HS), inhibits the ...
Administration of multipotent mesenchymal stromal cells restores liver regeneration and improves liver function in obese mice with hepatic steatosis after partial hepatectomy
(BioMed Central, 2017)
Background: The liver has the remarkable capacity to regenerate in order to compensate for lost or damaged
hepatic tissue. However, pre-existing pathological abnormalities, such as hepatic steatosis (HS), inhibits the ...
Identification of hepatic progenitor cells in the canine fetal liver
(Elsevier B.V., 2020-12-01)
The liver plays essential roles in human and animal organisms, such as the storage, release, metabolism, and elimination of various endogenous or exogenous substances. Although its vital importance, few treatments are yet ...
Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells
(Cell Press, 2020-06)
The availability of an autologous transplantable auxiliary liver would dramatically affect the treatment of liver disease. Assembly and function in vivo of a bioengineered human liver derived from induced pluripotent stem ...
Ultrasound analysis of a canine patient with renal disease and chronic liver disease undergoing treatment with intravenous stem cells
(Univ Federal Rural Pernambuco, 2011-12-01)
With the improvement in quality of life of animals, it is increasingly frequent clinical care of elderly patients, which present renal disorders, including chronic renal failure. Recent studies report the use of stem cells ...
Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection
(Springer Nature, 2019)
The exoerythrocytic stage of Plasmodium infection is a critical window for prophylactic intervention. Using genome-wide dual RNA sequencing of flow-sorted infected and uninfected hepatoma cells we show that the human mucosal ...